Results 111 to 120 of about 10,440,044 (293)
Exploring the Issues: An Evaluation Literature Review [PDF]
, 2016 Finding ways to make evaluation more meaningful and more useful has been a key theme in the evaluation literature since the discipline began, and there is no shortage of discussion around improving evaluation among nonprofit practitioners.
Andrew Taylor, Ben Liadsky
core
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Virtual teams: A literature review [PDF]
In the competitive market, virtual teams represent a growing response to the need for fasting time-to-market, low-cost and rapid solutions to complex organizational problems.
Ahmed, Shamsuddin +2 more
core +1 more source
Wakefield Area Working Evaluation Framework - Literature Review [PDF]
, 2012 The Wakefield Metropolitan District Council (MDC) Area Working programme offers a radical and innovative approach to service improvement and redesign with the aim of better meeting community needs and addressing inequalities. Community participation is a
South, J, Warwick-Booth, L
core
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Traffic, diesel and asthma : a literature review [PDF]
, 2007 This article details the major pollutants from motor vehicle exhaust, mainly particulate matter, nitrogen dioxide and polycyclic aromatic hydrocarbons.
Schembri, Gabriel
core
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source