Results 131 to 140 of about 10,682,661 (327)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

LONELINESS IN THE ELDERLY– LITERATURE REVIEW

open access: yesAnthropological Researches and Studies
Objectives. This study aims to conduct an in-depth analysis of the intricate facets of loneliness to acquire a deeper comprehension of this emotional state.
Cristina VLAICU
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Infertility and Health Related Quality of Life: Minireview of the Literature

open access: yesJournal of Family and Reproductive Health, 2007
Objective: Since health related quality of life is an important issue for infertile couples a review was conducted to examine the literature. Materials and methods: This was a minireview of the literature covering all full publications that have been ...
Ali Montazeri
doaj  

Sustainability Adoption through Sustainable Human Resource Management: A Systematic Literature Review and Conceptual Framework

open access: gold, 2020
Anil Kumar   +4 more
openalex   +1 more source

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