Results 121 to 130 of about 4,153,159 (336)

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Assessing the Validity and Accuracy of Artificial Intelligence Technologies for Identifying Relevant Literature in Dentistry

Journal of Nature and Science of Medicine
Introduction: Health care sector, across its numerous domains, has been employing artificial intelligence (AI), encompassing a wide range of tasks involving the various stages of complexity.
Ameena M Siyad, A. S. Akhila, Subramaniam Ramanarayanan, Shabil Mohamed Mustafa, Jesline Merly James, Priya Babu   +5 more
doaj   +1 more source

Methodology Used to Assess Acceptability of Oral Pediatric Medicines: A Systematic Literature Search and Narrative Review [PDF]

, 2017
Punam Mistry, Hannah Batchelor, Hannah Batchelor   +2 more
openalex   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Literature horizon scan for new scientific data on plants and their products obtained by new genomic techniques (January 2022 to May 2025)

EFSA Journal
The European Food Safety Authority has issued several scientific opinions on plants obtained through certain new genomic techniques (NGTs) following requests received by the European Commission.
European Food Safety Authority (EFSA), Martina Bonatti, Paolo Lenzi, Aleksandra Lewandowska, Irene Pilar Munoz Guajardo, Nikoletta Papadopoulou, Tommaso Raffaello, Elena Sánchez‐Brunete   +7 more
doaj   +1 more source

pubCounteR: an R package for interrogating published literature for experimentally-derived gene lists within a user-defined biological context

Frontiers in Bioinformatics
Basic and clinical biomedical research relies heavily on modern large-scale datasets that include genomics, transcriptomics, epigenomics, metabolomics, and proteomics, among other “Omics”. These research tools very often generate lists of candidate genes
Marina Leer, Marina Leer, George A. Soultoukis, George A. Soultoukis, Markus Jähnert, Markus Jähnert, Masoome Oveisi, Masoome Oveisi, Dirk Walther, Tim J. Schulz, Tim J. Schulz, Tim J. Schulz   +11 more
doaj   +1 more source

Adapting Search Theory to Networks [PDF]

, 2001
The CSE is interested in the general problem of locating objects in networks. Because of their exposure to search theory, the problem they brought to the workshop was phrased in terms of adapting search theory to networks.
Alspach, Brian
core  

A Model of Optimal Network Structure for Decentralized Nearest Neighbor Search

, 2017
One of the approaches for the nearest neighbor search problem is to build a network which nodes correspond to the given set of indexed objects. In this case the search of the closest object can be thought as a search of a node in a network.
Batsyn, Mikhail, Ponomarenko, Alexander, Utkina, Irina   +2 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Collaborating with AI in literature search-An important frontier. [PDF]

Hepatol Commun, 2023
Enomoto M, Tseng CH, Hsu YC, Thuy LTT, Thuy LTT, Nguyen MH.   +5 more
europepmc   +1 more source