Results 131 to 140 of about 18,300,927 (344)
Basic and clinical biomedical research relies heavily on modern large-scale datasets that include genomics, transcriptomics, epigenomics, metabolomics, and proteomics, among other “Omics”. These research tools very often generate lists of candidate genes
Marina Leer +11 more
doaj +1 more source
Educating the Public Health Workforce: A Scoping Review
The aim of this scoping review was to identify and characterize the recent literature pertaining to the education of the public health workforce worldwide.
Donghua Tao +3 more
doaj +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Paramedic literature search filters: optimised for clinicians and academics
BackgroundSearch filters aid clinicians and academics to accurately locate literature. Despite this, there is no search filter or Medical Subject Headings (MeSH) term pertaining to paramedics. Therefore, the aim of this study was to create two filters to
A. Olaussen +4 more
semanticscholar +1 more source
Literature search terms used in the study (Search 2).
Literature search terms used in the study (Search 2).
Natalie M. D’Silva (16649067) +6 more
core +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
SciRide Finder: a citation-based paradigm in biomedical literature search
There are more than 26 million peer-reviewed biomedical research items according to Medline/PubMed. This breadth of information is indicative of the progress in biomedical sciences on one hand, but an overload for scientists performing literature ...
Adam Volanakis, K. Krawczyk
semanticscholar +1 more source
A review of the Tabu Search Literature on Traveling Salesman Problems [PDF]
The Traveling Salesman Problem (TSP) is one of the most widely studied problems inrncombinatorial optimization. It has long been known to be NP-hard and hence research onrndeveloping algorithms for the TSP has focused on approximate methods in addition ...
Sumanta Basu, Ghosh, Diptesh
core
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source

