Results 31 to 40 of about 4,082,281 (336)
The drug safety information in domestic medical literature
Current Issues in Pharmacy and Medical Sciences, 2022 Medical literature is an important source of drug safety information relevant for signal detection, safety profile analysis and risk-benefit assessment.
Ochyra Bartlomiej +2 more
doaj +1 more source
Beyond Oncology: Question Prompt Lists in Healthcare—A Scoping Review Protocol
Methods and Protocols, 2020 Question prompt lists (QPL) are an instrument to promote patient participation in medical encounters by providing a set of questions patients can use during consultations. QPL have predominantly been examined in oncology. Less is known about their use in
Matthias Lukasczik +3 more
doaj +1 more source
Repeated Dosing of Ketamine in the Forced Swim Test: Are Multiple Shots Better Than One?
Frontiers in Psychiatry, 2021 The anesthetic drug ketamine has been successfully repurposed as an antidepressant in human subjects. This represents a breakthrough for clinical psychopharmacology, because unlike monoaminergic antidepressants, ketamine has rapid onset, including in ...
Ridge G. Weston +2 more
doaj +1 more source
Auditing Search Engines for Differential Satisfaction Across Demographics [PDF]
, 2017 Many online services, such as search engines, social media platforms, and digital marketplaces, are advertised as being available to any user, regardless of their age, gender, or other demographic factors.
Anderson, Ashton +5 more
core +2 more sources
A review of studies mapping (or cross walking) from non-preference based measures of health to generic preference-based measures [PDF]
, 2008 This paper presents a systematic review of current practice in mapping between nonpreference based measures and generic preference-based measures.
Brazier, J.E., Tsuchiya, A., Yang, Y.
core +2 more sources
RAD50 missense variants differentially affect the DNA damage response and mitotic progression
FEBS Letters, EarlyView.RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker +9 more
wiley +1 more source
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Results of literature search on dielectric properties and electron interaction phenomena related to spacecraft charging [PDF]
, 1977 The objective of the literature search was to determine the required material properties and electron interaction parameters needed for modeling charge buildup and breakdown in insulators. A brief overview of the results of the literature search is given.
Burke, E. A. +2 more
core +1 more source
FEBS Letters, EarlyView.Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia +5 more
wiley +1 more source
FEBS Letters, EarlyView.Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source