Results 51 to 60 of about 4,207,164 (296)
Systematic reviews are cumbersome yet essential to the epistemic process of medical science. Finding significant reports, however, is a daunting task because the sheer volume of published literature makes the manual screening of databases time-consuming.
Carlo Galli +2 more
doaj +1 more source
BackgroundAlthough largely preventable, cardiovascular diseases (CVDs) are the biggest cause of death worldwide. Common complex cardiovascular disorders (e.g., coronary heart disease, hypertonia, or thrombophilia) result from a combination of genetic ...
Szilvia Fiatal +4 more
doaj +1 more source
The drug safety information in domestic medical literature
Medical literature is an important source of drug safety information relevant for signal detection, safety profile analysis and risk-benefit assessment.
Ochyra Bartlomiej +2 more
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Analysis Of The Girth For Regular Bi-partite Graphs With Degree 3 [PDF]
The goal of this paper is to derive the detailed description of the Enumeration Based Search Algorithm from the high level description provided in [16], analyze the experimental results from our implementation of the Enumeration Based Search Algorithm ...
Nittoor, Vivek S, Suda, Reiji
core
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
New perspectives on Web search engine research [PDF]
Purpose–The purpose of this chapter is to give an overview of the context of Web search and search engine-related research, as well as to introduce the reader to the sections and chapters of the book.
Lewandowski, Dirk
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Introducing CRIS—A unified framework for systematic literature searches across disciplines
IntroductionCross-disciplinary research approaches have become more necessary in light of the increasing global and societal challenges. As different forms of collaboration emerge, cross-disciplinary systematic reviews that integrate these approaches are
Celina Ciemer +4 more
doaj +1 more source
Petroleum hydrocarbons in fresh waters: a preliminary desk study and bibliography [PDF]
A literature survey was carried out into the effects of petroleum hydrocarbons in freshwater, from the toxicity, biodegradability and concentration aspects.
Horne, J.E.M. +3 more
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