Results 71 to 80 of about 9,864,870 (342)

Application of Single-Nucleotide Polymorphism-Related Risk Estimates in Identification of Increased Genetic Susceptibility to Cardiovascular Diseases: A Literature Review

open access: yesFrontiers in Public Health, 2018
BackgroundAlthough largely preventable, cardiovascular diseases (CVDs) are the biggest cause of death worldwide. Common complex cardiovascular disorders (e.g., coronary heart disease, hypertonia, or thrombophilia) result from a combination of genetic ...
Szilvia Fiatal   +4 more
doaj   +1 more source

Search terms used for literature search.

open access: yes, 2022
Search terms used for literature search.
Mitchell R. L. Forrest (14019749)   +5 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Search terms used for electronic literature search.

open access: yes, 2023
Search terms used for electronic literature search.
Marcus Yung (4409020)   +5 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

KI-Tools für die wissenschaftliche Literaturrecherche: Potenziale, Problematiken, Didaktik und Zukunftsperspektiven

open access: yesBibliothek
Dieser Artikel stellt zwanzig KI-Tools vor, die speziell für die wissenschaftliche Literatursuche konzipiert wurden. Anschließend werden didaktische Herausforderungen bei Schulungen zur Recherche mit KI-Tools diskutiert. Am Ende folgt ein Ausblick darauf,
Lahrsow Miriam
doaj   +1 more source

Introducing CRIS—A unified framework for systematic literature searches across disciplines

open access: yesFrontiers in Public Health
IntroductionCross-disciplinary research approaches have become more necessary in light of the increasing global and societal challenges. As different forms of collaboration emerge, cross-disciplinary systematic reviews that integrate these approaches are
Celina Ciemer   +4 more
doaj   +1 more source

Beyond Oncology: Question Prompt Lists in Healthcare—A Scoping Review Protocol

open access: yesMethods and Protocols, 2020
Question prompt lists (QPL) are an instrument to promote patient participation in medical encounters by providing a set of questions patients can use during consultations. QPL have predominantly been examined in oncology. Less is known about their use in
Matthias Lukasczik   +3 more
doaj   +1 more source

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