Results 81 to 90 of about 4,207,164 (296)

Assessing the Validity and Accuracy of Artificial Intelligence Technologies for Identifying Relevant Literature in Dentistry

Journal of Nature and Science of Medicine
Introduction: Health care sector, across its numerous domains, has been employing artificial intelligence (AI), encompassing a wide range of tasks involving the various stages of complexity.
Ameena M Siyad, A. S. Akhila, Subramaniam Ramanarayanan, Shabil Mohamed Mustafa, Jesline Merly James, Priya Babu   +5 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

pubCounteR: an R package for interrogating published literature for experimentally-derived gene lists within a user-defined biological context

Frontiers in Bioinformatics
Basic and clinical biomedical research relies heavily on modern large-scale datasets that include genomics, transcriptomics, epigenomics, metabolomics, and proteomics, among other “Omics”. These research tools very often generate lists of candidate genes
Marina Leer, Marina Leer, George A. Soultoukis, George A. Soultoukis, Markus Jähnert, Markus Jähnert, Masoome Oveisi, Masoome Oveisi, Dirk Walther, Tim J. Schulz, Tim J. Schulz, Tim J. Schulz   +11 more
doaj   +1 more source

Educating the Public Health Workforce: A Scoping Review

Frontiers in Public Health, 2018
The aim of this scoping review was to identify and characterize the recent literature pertaining to the education of the public health workforce worldwide.
Donghua Tao, Connie J. Evashwick, Michal Grivna, Roger Harrison   +3 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Literature search

, 2019
The paper seeks to highlight the complexity of literature searching in online bibliographic databases and the importance of developing advanced search skills towards greater search efficiency. The lack of knowledge of the content, structure and operation of databases, poor search skills, and superficiality in assessing search results are discussed as ...
openaire   +2 more sources

Assessing the Counterfactual: The Efficacy of Drug Interdiction Absent Racial Profiling [PDF]

, 2005
This Article investigates the costs and benefits of racial profiling in the context of drug interdiction. I begin by reviewing the empirical economic and civil rights literature regarding the existence and rationality of racial profiling and then build ...
Barnes, Katherine Y.
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Literature horizon scan for new scientific data on plants and their products obtained by new genomic techniques (January 2022 to May 2025)

EFSA Journal
The European Food Safety Authority has issued several scientific opinions on plants obtained through certain new genomic techniques (NGTs) following requests received by the European Commission.
European Food Safety Authority (EFSA), Martina Bonatti, Paolo Lenzi, Aleksandra Lewandowska, Irene Pilar Munoz Guajardo, Nikoletta Papadopoulou, Tommaso Raffaello, Elena Sánchez‐Brunete   +7 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source