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Journal of Market Access & Health Policy, 2021 Background: The practice of non-medical switch (NMS) from a reference biological (originator) to a biosimilar is widely accepted in some countries. However, there is little documentation on the impact of NMS from one originator to another originator ...
Knut Stavem
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A plea for minimally biased naturalistic philosophy [PDF]
, 2019 Naturalistic philosophers rely on literature search and review in a number of ways and for different purposes. Yet this article shows how processes of literature search and review are likely to be affected by widespread and systematic biases.
Polonioli, Andrea
core
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Computer-based literature search in medical institutions in India
Annals of Indian Academy of Neurology, 2007 Aim: To study the use of computer-based literature search and its application in clinical training and patient care as a surrogate marker of evidence-based medicine.
Kalita Jayantee +2 more
doaj
Journal of the Medical Library Association, 2020 Objective: The authors reviewed educational interventions for improving literature searching skills in the health sciences. Methods: We performed a scoping review of experimental and quasi-experimental studies published in English and German ...
Julian Hirt +5 more
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FEBS Letters, EarlyView.PARP‐1 is a key enzyme in the DNA damage response, and its inhibition induces cancer cell death via synthetic lethality. Au(I)‐based drugs, such as aurothioglucose and sodium aurothiomalate, block PARP‐1's DNA‐dependent activity by targeting its zinc finger domains.
Uliana Bashtanova, Melinda Jane Duer
wiley +1 more source
Cross Validation Of Neural Network Applications For Automatic New Topic Identification [PDF]
, 2005 There are recent studies in the literature on automatic topic-shift identification in Web search engine user sessions; however most of this work applied their topic-shift identification algorithms on data logs from a single search engine.
Spink, Amanda +3 more
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Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Em busca de compreensões sobre os objetos de aprendizagem na educação matemática por meio de uma revisão sistemática de literatura<br>In search of understanding about learning objects in mathematics education through a systematic literature review [PDF]
, 2021 Marcelo Souza Motta +1 more
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