Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
PubDNA Finder in a Nutshell. Searching the Life Sciences Literature with Sequences of Nucleic Acids [PDF]
, 2011 Biomedical researchers and clinicians working with molecular technologies in routine clinical practice often need to review the available literature to gather information regarding specific sequences of nucleic acids. This includes, for instance, finding
García Remesal, Miguel
core
Journal of the Medical Library AssociationObjective: There is little research available regarding the instructional practices of librarians who support students completing knowledge synthesis projects.
Glyneva Bradley-Ridout +6 more
doaj +1 more source
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Searching the literature for studies for a systematic review:Part 5: Beyond the standard electronic databases [PDF]
, 2019 In the past few issues, we have looked at how to construct a search for the main electronic databases. However, to get a very sensitive search and to combat publication bias, you may need to go further than looking at the standard databases.
Littlewood, Anne, Kloukos, Dimitrios
core +1 more source
Video killed the multiple-choice quiz: capturing pharmacy students' literature searching skills using a screencast video assignment. [PDF]
J Med Libr Assoc, 2021 Jones EP, Wisniewski CS.
europepmc +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Evaluation of literature searching tools for curation of mismatch repair gene variants in hereditary colon cancer. [PDF]
Adv Genet (Hoboken), 2021 Kaushik V, Plazzer JP, Macrae F.
europepmc +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Text Extraction and Web Searching in a Non-Latin Language [PDF]
Recent studies of queries submitted to Internet Search Engines have shown that non-English queries and unclassifiable queries have nearly tripled during the last decade. Most search engines were originally engineered for English. They do not take full
Lazarinis, Fotis
core +4 more sources