Results 71 to 80 of about 7,014,090 (286)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Searching the midwifery literature

, 1994
The skill of searching the literature is both easy to learn and very useful. Tracking down that elusive article or finding all there is to know on a particular topic gives a great sense of achievement.
Tricia Murphy-Black
core   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Optimal random Levy-loop searching: new insights into the searching behaviours of central-place foragers

, 2008
A random Lévy-looping model of searching is devised and optimal random Lévy-looping searching strategies are identified for the location of a single target whose position is uncertain. An inverse-square power law distribution of loop lengths is shown to
Reynolds, A. M., A. M. Reynolds
core   +1 more source

Efficiency of searching the grey literature in palliative care. [PDF]

, 2001
A systematic review into palliative care team effectiveness was undertaken which has, inherent in its methodology, grey literature searching. Over 100 letters were written to a systematically chosen range of service providers, commissioners, and experts ...
Douglas, H R, Higginson, J, Douglas, Hannah-Rose, Higginson, I J; id_orcid, Hook, K, Cook, Alison M., Higginson, IJ, Cook, Alison, Normand, C E, Edwards, Adrian G.K., Edwards, A G K, Goodwin, DM, Normand, Charles E., Cook, A M, Finlay, Ilora G., Finlay, IG, Higginson, Irene J., Cook, AM, Hood, K, Goodwin, D M, Normand, CE, Edwards, AG, Douglas, HR, Edwards, Adrian G., Hood, Kerenza, Finlay, E G, Goodwin, Danielle M.   +26 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

The Contributions of MEDLINE, Other Bibliographic Databases and Various Search Techniques to NICE Public Health Guidance

Evidence Based Library and Information Practice, 2015
Objective – To make recommendations for the National Institute for Health and Care Excellence (NICE) on the factors to consider when choosing databases and search techniques when producing systematic reviews to support public health guidance development.
Paul Levay, Michael Raynor, Daniel Tuvey
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

How do Various Fugitive Literature Searching Methods Impact the Comprehensiveness of Literature Uncovered for Systematic Review?

, 2000
BACKGROUND: As the production of grey literature (GL) increases, the methods used to uncover such literature evolve and are now included as part of the "standard" fugitive search strategy used by many technology assessment organizations.
Helmer, Diane (BCOHTA), Green, Carolyn (BCOHTA), GreyNet, Grey Literature Network Service, Savoie, Isabelle (BCOHTA)   +3 more
core  

Leveraging Grey Literature – Capitalizing on Value and the Return on Investment

, 2016
The method of approach is a cumulative case study from 2003 onwards of a select number of information products and services provided by GreyNet. Each were introduced to serve the interests of the grey literature community and their production and supply ...
Farace, Dr. D. (GreyNet International, Grey Literature Network Service)
core   +1 more source