Results 51 to 60 of about 7,014,090 (286)

Managing expectations: an online resource to support health sciences students with their dissertation

Journal of Learning Development in Higher Education
This presentation shared how we introduced a literature searching online guide, designed specifically to support health sciences students who are working on their dissertation.
Charlotte Allen
doaj   +1 more source

Development and validation of a search filter to identify equity-focused studies: reducing the number needed to screen

BMC Medical Research Methodology, 2018
Background Health inequalities, worse health associated with social and economic disadvantage, are reported by a minority of research articles. Locating these studies when conducting an equity-focused systematic review is challenging due to a deficit in ...
Stephanie L Prady, Eleonora P Uphoff, Madeleine Power, Su Golder   +3 more
doaj   +1 more source

Edukative Interventionen zur Verbesserung systematischer Recherchefähigkeiten – Diskussion der Ergebnisse eines Scoping Reviews

GMS Medizin – Bibliothek – Information, 2020
As a basis for systematic reviews and thus for evidence-based clinical decision making, conducted literature searches often show methodological weaknesses and errors.
Nordhausen, Thomas, Hirt, Julian
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Evidence based medicine (EBM) simulation: a novel and practice-relevant approach to teaching real-time literature searching to emergency medicine residents

, 2020
Introduction: Evidence-based medicine (EBM) and literature searching skills are competencies within the Emergency Medicine (EM) residency curriculum. Previously in our residency program, a librarian-taught literature searching instruction comprised a ...
Colmers-Gray, Isabelle, Tan, Maria C., Ha, David J, Dong, Sandy L   +3 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Understanding the performance of geographic limits on Web of Science Core Collection databases, using the United Kingdom as an example

Journal of the Medical Library Association
Objective: To consider the approaches within Web of Science Core Collection (WoSCC) databases for limiting geographically. To compare the limits to an adaptation of NICE’s UK MEDLINE filter for use on WoSCC databases.
Helen A. Fulbright, Claire Stansfield
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

The case for consistent use of medical eponyms by eliminating possessive forms

Journal of the Medical Library Association, 2018
The objective of this commentary is to highlight the pervasive usage of both forms of medical eponyms in medical literature amongst prestigious medical journals indexed in the PubMed database. This use of eponyms poses a source of confusion in literature
Kwabena Ayesu, Brenda Nguyen, Stephanie Harris, Steve Carlan   +3 more
doaj   +1 more source