Results 91 to 100 of about 1,182,968 (316)

HOW ASSESS DRUGS IN THE TREATMENT OF ACUTE BIPOLAR MANIA ?

Frontiers in Pharmacology, 2013
Bipolar affective disorder is a serious mental disease associated with significant morbidity and mortality. Good-quality research available to guide treatment strategies remains insufficient, particularly with regard to manic or hypomanic episodes.
Michel eBourin, Florence eThibaut
doaj   +1 more source

Lithium monotherapy associated longitudinal effects on resting state brain networks in clinical treatment of bipolar disorder

Bipolar Disorders, 2018
Lithium is one of the most effective and specific treatments for bipolar disorder (BP), but the neural mechanisms by which lithium impacts symptoms remain unclear.
J. Spielberg, Melanie A. Matyi, H. Karne, A. Anand   +3 more
semanticscholar   +1 more source

Bone‐Derived dECM Hydrogels Support Tunable Microenvironments for In Vitro Osteogenic Differentiation

Advanced Healthcare Materials, EarlyView.
A tunable methacrylated decellularized bone matrix hydrogel (dECM‐MA) is developed to support 3D culture of human osteoblasts. The hydrogel preserves bone‐specific ECM cues and allows precise control over mechanical properties. This system provides a customizable platform for studying osteogenic differentiation and modeling bone tissue environments for
Minne Dekker, Luke Hipwood, Akhilandeshwari Ravichandran, Dietmar W. Hutmacher, Christoph Meinert, Jacqui McGovern   +5 more
wiley   +1 more source

Psychotropic drugs and bone

Bolʹ, Sustavy, Pozvonočnik
The purpose of this article is to provide an overview of the effects of psychotropic medications on bone metabolism, bone mineral density (BMD), and fracture risk. Methods. The literature search was carried out in PubMed.
R.W. Gasser, H. Resch
doaj   +1 more source

Biologically Active Implants Prevent Mortality in a Mouse Sepsis Model

Advanced Healthcare Materials, EarlyView.
A modular, triple‐action titanium implant is developed to prevent implant‐associated infections by repelling bacteria, killing pathogens, and enhancing tissue integration. Coatings with phage cocktails targeting P. aeruginosa and S. aureus show significant bacterial reduction and improved survival in a mouse sepsis model.
Martin Stark, Fereshteh Bayat, Sara Rahmani, Mathura Thirugnanasampanthar, Taylor Kramer, Elise Schwarz, David Wilson, Jeffrey I. Weitz, Zeinab Hosseinidoust, Tohid F. Didar   +9 more
wiley   +1 more source

Lithium Versus Other Mood-Stabilizing Medications in a Longitudinal Study of Youth Diagnosed With Bipolar Disorder [PDF]

, 2019
Danella Hafeman, Brian Rooks, John Merranko, Fangzi Liao, Mary Kay Gill, Tina R. Goldstein, Rasim Somer Diler, Neal D. Ryan, Benjamin I. Goldstein, David Axelson, Michael Strober, Martin B. Keller, Jeffrey Hunt, Heather Hower, Lauren M. Weinstock, Shirley Yen, Boris Birmaher   +16 more
openalex   +1 more source

Miniaturized Wireless tDCS With Concentric Electrodes for Targeted Cortical Stimulation in Freely Moving Mice

Advanced Healthcare Materials, EarlyView.
This study introduces a wireless and miniaturized concentric‐electrode tDCS (CE‐tDCS) system tailored for freely moving mice. The device enables focal and multi‐site cortical stimulation via a lightweight, Bluetooth‐controlled platform. By integrating local neuromodulation with real‐time behavioral analysis, the system provides a robust tool for ...
Minseok Kim, Sehwan Park, Haeyun Lee, Giheon Kim, Namsun Chou, Hyogeun Shin   +5 more
wiley   +1 more source

Prospective cohort study of early biosignatures of response to lithium in bipolar-I-disorders: overview of the H2020-funded R-LiNK initiative

International Journal of Bipolar Disorders, 2019
Background Lithium is recommended as a first line treatment for bipolar disorders. However, only 30% of patients show an optimal outcome and variability in lithium response and tolerability is poorly understood.
Jan Scott, Diego Hidalgo-Mazzei, Rebecca Strawbridge, Allan Young, Matthieu Resche-Rigon, Bruno Etain, Ole A. Andreassen, Michael Bauer, Djamila Bennabi, Andrew M. Blamire, Fawzi Boumezbeur, Paolo Brambilla, Nadia Cattane, Annamaria Cattaneo, Marie Chupin, Klara Coello, Yann Cointepas, Francesc Colom, David A. Cousins, Caroline Dubertret, Edouard Duchesnay, Adele Ferro, Aitana Garcia-Estela, Jose Goikolea, Antoine Grigis, Emmanuel Haffen, Margrethe C. Høegh, Petter Jakobsen, Janos L. Kalman, Lars V. Kessing, Farah Klohn-Saghatolislam, Trine V. Lagerberg, Mikael Landén, Ute Lewitzka, Ashley Lutticke, Nicolas Mazer, Monica Mazzelli, Cristina Mora, Thorsten Muller, Estanislao Mur-Mila, Ketil Joachim Oedegaard, Leif Oltedal, Erik Pålsson, Dimitri Papadopoulos Orfanos, Sergi Papiol, Victor Perez-Sola, Andreas Reif, Philipp Ritter, Roberto Rossi, Thomas Schulze, Fanny Senner, Fiona E. Smith, Letizia Squarcina, Nils Eiel Steen, Pete E. Thelwall, Cristina Varo, Eduard Vieta, Maj Vinberg, Michele Wessa, Lars T. Westlye, Frank Bellivier   +60 more
doaj   +1 more source

Risks and benefits of psychotropic medication in pregnancy: cohort studies based on UK electronic primary care health records.

Health Technology Assessment, 2016
BACKGROUND Although many women treated with psychotropic medication become pregnant, no psychotropic medication has been licensed for use in pregnancy. This leaves women and their health-care professionals in a treatment dilemma, as they need to balance ...
I. Petersen, R. L. McCrea, C. Sammon, D. Osborn, S. Evans, P. Cowen, N. Freemantle, I. Nazareth   +7 more
semanticscholar   +1 more source

Mesoporous Bioactive Glasses: A Powerful Tool in Tissue Engineering and Drug Delivery

Advanced Healthcare Materials, EarlyView.
This work is a comprehensive revision of bioactive glasses (BGs), pioneered by Prof. L.L. Hench, which are key in bone repair and regenerative medicine. Sol–gel methods and mesoporous designs enhanced their bioactivity, ions, and drug delivery. BGs now support gene therapy and 3D‐printed scaffolds, enabling personalized, multifunctional treatments in ...
Natividad Gómez‐Cerezo, Daniel Lozano, Antonio J. Salinas, María Vallet‐Regí   +3 more
wiley   +1 more source