Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong +5 more
wiley +1 more source
Persistent Tremor in Bipolar Disorder: A Case Report of Idiopathic Parkinson's Disease Superimposed on Lithium and Antipsychotic Effects. [PDF]
Jetter E, Valle D, Nolasco D, Carr B.
europepmc +1 more source
Spatial‐Wavelength Multiplexing Error‐Controlled Photonic Analog Computing System
A novel photonic integrated circuit prototype implementing the concept of general‐purpose analog computing and demonstrate its capability in radio frequency applications. The chip features a multichannel architecture and performs fully optical analog computation with frequency‐domain parallel processing. An FPGA‐based error‐correction algorithm aims to
Tao Zhu +15 more
wiley +1 more source
Lithium toxicity following a change from semaglutide to tirzepatide for weight loss management. [PDF]
Burson JR, Leung JG.
europepmc +1 more source
Machine Learning Discovery of Record‐Low Lattice Thermal Conductivity in Double Perovskites
A deep learning interatomic potential is introduced to predict forces for computing phonon properties and thermal transport behavior in double perovskites. Screening 9,709 compounds identifies 1,597 stable materials, and Boltzmann transport calculations including both three and four‐phonon scattering suggests a record‐low lattice thermal conductivity ...
Md Zaibul Anam +3 more
wiley +1 more source
A Significant Decline of Glomerular Filtration Rate in the Majority of Long-Term Lithium Users: Results of a Dutch Prospective 10-Year Cohort Study. [PDF]
van der Aa MJ +9 more
europepmc +1 more source
Borophene: Crucial Challenges and the Way Forward
This review explores the challenges and progress in borophene research, focusing on synthesis strategies, structural properties, and potential applications. It highlights key experimental breakthroughs, discusses theoretical insights into borophene's unique features, and addresses pathways for overcoming stability and scalability issues.
Zhixuan Li +3 more
wiley +1 more source
Lithium-induced hypokalemic periodic paralysis: A rare and life-threatening complication in bipolar disorder management. [PDF]
Balagopal A, Kumar S, Shetty A.
europepmc +1 more source
A multifunctional injectable microsphere system is fabricated via UV‐assisted microfluidic cross‐linking, integrating nanozyme‐based ROS scavenging, sustained dexamethasone release, and stem cell delivery. Upon IA injection, the microspheres adapt to joint stress, suppress inflammation, and promote cartilage regeneration, offering a minimally invasive ...
Xiaochen Feng +10 more
wiley +1 more source
Three years of medication-use sequences in incident bipolar disorder in Sweden reveal divergent patterns in native-born and immigrant populations. [PDF]
Kautzky A +8 more
europepmc +1 more source

