Results 131 to 140 of about 7,854 (219)

The RNA‐Binding Protein PARN Remodeled 3′ UTR Structure Defines Poly(A)‐Loading Sites to Mediate Immunoglobulin Homeostasis

Advanced Science, EarlyView.
ABSTRACT Class Switch Recombination (CSR) is essential for generating high‐affinity antibody isotypes from IgM during adaptive humoral responses. Despite well‐established roles for various transcription factors, whether CSR is subject to dedicated post‐transcriptional control represents a significant gap in knowledge.
Siyuan Sun, Chen Yang, Xiaoyu Wang, Naijing Hu, Shengyao Zhang, Xinchun Li, Yu Chen, Jianan Zhai, Xiangfeng Tang, Wei Lu, Chenxu Lu, Changchang Cao, Weiru Yu, Wenhao Wu, Xiaonan Nie, Fengchao Wang, Bing Fang, Fazheng Ren, Yixuan Li, Juan Chen   +19 more
wiley   +1 more source

Detection and Genetic Characterization of Red-Spotted Grouper Nervous Necrosis Virus and a Novel Genotype of Nervous Necrosis Virus in Black Sea Bass from the U.S. Atlantic Coast. [PDF]

Viruses
Lovy J, Abbadi M, Toffan A, Das N, Neugebauer JN, Batts WN, Clarke PJ.   +6 more
europepmc   +1 more source

Local Polarization Unit Engineering Enables Ultrahigh Energy Density in NBT‐Based High‐Entropy Ceramic Capacitors

Advanced Science, EarlyView.
Herein, we demonstrate a breakthrough in dielectric energy storage by engineering local polarization units in high‐entropy multilayer ceramic capacitors (MLCCs). The optimized MLCCs achieve an ultrahigh recoverable energy density of 18.2 J cm−3 with 91% efficiency, coupled with exceptional thermal stability and fatigue resistance.
Shiyu Zhou, Yucheng Zhou, Linhai Li, A. Pelaiz‐Barranco, Xuefeng Chen, Genshui Wang, Yiwei Chen, Rongjiang Wang, Konstantin Nefedev, Tengfei Hu, Dawei Wang, Tongqing Yang   +11 more
wiley   +1 more source

Pro-inflammatory LPS drives production and release of the chemokine MCP-1 in human coronary artery smooth muscle cells. [PDF]

Mol Cell Biochem
Bankell E, Gidlöf O, Nilsson BO.
europepmc   +1 more source

A Microgel Platform Enables Site‐Specific Intestinal Delivery of Lactoferrin, Improving its Bioavailability for Targeted Alleviating Liver Injury and Colitis

Advanced Science, EarlyView.
This work first time reports an eco‐friendly desert plant food‐based polysaccharide ASKP microgels which have intestinal site‐specific release properties which can achieve small‐intestine or colon targeting capability via different cross‐linking chemistry.
Huiling Yan, Yixuan Li, Shanan Chen, Pengcheng Du, Kaiwen Wu, Hui Zhang, Kasper Hettinga, Lina Zhang, Gergely Toldi, Fazheng Ren, Yuan Li   +10 more
wiley   +1 more source

Identification of the client-binding site on the Golgi membrane protein adaptor Vps74/yGOLPH3. [PDF]

iScience
Lesniak AM, Ye Z, Banfield DK.
europepmc   +1 more source

Mixed‐Coordination Electrolytes With Molecular Additives for Robust Interphases in High‐Voltage Rechargeable Magnesium Batteries

Advanced Science, EarlyView.
A mixed‐coordination electrolyte (MCE) combined with a molecular additive (MCE‐MA) promotes pseudo ion pair (pIP) formation within a solvent‐separated ion pair (SSIP)–rich environment, enabling a robust interphase that significantly improves the cycle performance of high‐voltage rechargeable magnesium batteries (RMBs).
Dedy Setiawan, Toshihiko Mandai
wiley   +1 more source

Cross-species transmission of host adaptation of feline leukemia virus between domestic cats and the wild felid Leopardus guigna. [PDF]

Vet Res
Castillo-Aliaga C, Sacristán I, Stuardo CJ, Napolitano C, Hidalgo-Hermoso E, Tarlinton RE.   +5 more
europepmc   +1 more source

SIRT6‐Mediated Deacetylation of ATF3 Promotes Silica‐Induced Lung Fibrosis by Enhancing its Nuclear Import via Binding to Importin α

Advanced Science, EarlyView.
SIRT6‐mediated ATF3 acetylation drives MGARP transcription and mitochondrial dysfunction in macrophages, promoting macrophage senescence and pulmonary fibrosis. Mechanistically, HSP70/Importin α competitively binds to ATF3, modulating its nuclear translocation.
Demin Cheng, Wenxia Bu, Fengxu Wang, Yueyuan Jin, Rongzhu Liu, Rui Zhao, Xuehai Wang, Mengna Jiang, Jinping Shen, Xinhang Cheng, Zuming Chen, Li Zhu, Jinlong Li, Zhenzhong Ge, Shichen Miao, Haotian Xu, Xiaoyu Zhou, Dongming Wang, Xinyuan Zhao   +18 more
wiley   +1 more source

Density and Coexistence Patterns of an Apex Carnivore (Panthera pardus) and a Mesocarnivore (Caracal aurata) in Northern Congo Forests. [PDF]

Animals (Basel)
Tossens S, Woodgate Z, Doucet JL, Henschel P, André A, Michaux J, Drouilly M.   +6 more
europepmc   +1 more source