Results 91 to 100 of about 1,319,093 (299)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The Astrophysical JournalAmong the most puzzling early discoveries of JWST are “little red dots” (LRDs), compact red sources that host broad Balmer emission lines, and in many cases exhibit a “V-shaped” change in slope in the rest-optical.
David J. Setton +20 more
doaj +1 more source
, 2006 In this manuscript the theory and some phenomena associated with the Little Effect are introduced as the spin induced orbital dynamics of confined fermions under strong magnetic and thermal environments.
Reginald B. Little
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Repositioning of the brand My Little Pony on the czech market
, 2019 The diploma thesis deals with the repositioning of the brand My Little Pony, under which portfolio come primarily plastic and plush toy ponies. The aim of the thesis is to design a proposal for implementation of the new positioning strategy of My Little ...
Staňková, Silvie
core
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Analysis of Marketing Communication of Hostel Little Quarter
, 2019 Bakalářská práce se zabývá marketingovou komunikací hostelu Little Quarter, který se nachází v centru Prahy. Jejím cílem je navrhnout doporučení, která povedou k zefektivnění marketingové komunikace.
Drbohlav, Václav
core
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Intro -- Title -- Copyright -- Contents -- Part One -- Preface -- I. Playing Pilgrims -- II. A Merry Christmas. -- III. The Laurence Boy. -- IV. Burdens. -- V. Being Neighborly. -- VI. Beth Finds the Palace Beautiful. -- VII. Amy's Valley of Humiliation.
Alcott, Louisa May., Merrill, Frank T.
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The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source