Results 71 to 80 of about 1,319,093 (299)

Multiscale Geometric Methods for Data Sets I: Multiscale SVD, Noise and Curvature

open access: yes, 2017
Large data sets are often modeled as being noisy samples from probability distributions μ in RD, with D large. It has been noticed that oftentimes the support M of these probability distributions seems to be well-approximated by low-dimensional sets ...
MAGGIONI, MAURO   +2 more
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Anthelia Holt, Matoaca, VA, to "Dear Little Friend," Lottie V. Clark, Namozine, VA., 21 November 1888

open access: yes, 1888
Begs her "Dear Little Friend" to visit her for Christmas, and describes the festivities planned; sends congratulations to her Uncle Dibbrel on his upcoming ...
Holt, Anthelia
core  

A cross-sectional study of the Birmingham Vasculitis Activity Score version 3 in systemic vasculitis. [PDF]

open access: yes, 2010
OBJECTIVE: Assessment of disease activity in vasculitis can be achieved using the BVAS, a clinical checklist of relevant symptoms, signs and features of active disease. The aim of this study was to revalidate the BVAS version 3 (BVAS v. 3) in a cohort of
Suppiah, Ravi   +94 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

The contest of the causer contender and the agent defender

open access: yesLanguage and Cognition
Skilled and impaired language users can fail to understand sentences with noncanonical thematic role ordering. To advance understanding of the cause of the difficulty, we compared noncanonically ordered, object-experiencer-verb (OE) sentences to ...
Margaret Kathleen Ryan   +4 more
doaj   +1 more source

The use of real-world contextual framing in UK university entrance level mathematics examinations

open access: yes, 2010
Although there has been considerable research into real-world contexts in elementary mathematics, little work has been done at a more advanced, post-16 level.
Little, Christopher Thomas
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Grammatical Constraints on the Borrowing of Nouns and Verbs in Urdu and English

open access: yesSAGE Open, 2019
The present study aims at establishing grammatical constraints on the borrowing of nouns (Ns) and verbs (Vs) in Urdu and English by adopting Noam Chomsky’s Methodological Naturalism within the field of generative grammar as the theoretical framework of ...
Binish Maqsood   +3 more
doaj   +1 more source

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