Results 51 to 60 of about 123,927 (253)

Reducing Bias in Beta Regression Models Using Jackknifed Liu-Type Estimators: Applications to Chemical Data

Journal of Mathematics
In the field of chemical data modeling, it is common to encounter response variables that are constrained to the interval (0, 1). In such cases, the beta regression model is often a more suitable choice for modeling.
Solmaz Seifollahi, Hossein Bevrani, Olayan Albalawi   +2 more
doaj   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Prognostic Implications of Sleep Architecture for Patients Admitted to the Intensive Care Unit With Status Epilepticus

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Status epilepticus (SE) is associated with significant mortality. Sleep architecture may reflect normal brain function. Impaired sleep architecture is associated with poorer outcomes in numerous conditions. Here we investigate the association of sleep architecture in continuous EEG (cEEG) with survival in SE.
Ran R. Liu, Marcus C. Ng, Gavin P. Winston, Sabrina Schaly, Garima Shukla, Lysa Boissé Lomax   +5 more
wiley   +1 more source

An almost unbiased Liu-type estimator in the linear regression model

Communications in Statistics - Simulation and Computation, 2022
A biased estimator, compared to least squares estimators, is one of the most used statistical procedures to overcome the problem of multicollinearity. Liu-type estimators, which are biased estimators, are preferred in a wide range of fields. In this article, we propose an almost unbiased Liu-type (AUNL) estimator and discuss its performance under the ...
openaire   +2 more sources

Characterization of Clinical Phenotype to Glial Fibrillary Acidic Protein Concentrations in Alexander Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the concentration of glial fibrillary acidic protein (GFAP) in cerebrospinal fluid (CSF) and plasma in Alexander disease (AxD) and whether GFAP levels are predictive of disease phenotypes. Methods CSF and plasma were collected (longitudinally when available) from AxD participants and non‐AxD controls.
Amy T. Waldman, Asako Takanohashi, Joshua Y. Joung, Geraldine W. Liu, Kaley Arnold, Amy Pizzino, Walter Faig, Sarah Woidill, Sona Narula, Adeline L. Vanderver   +9 more
wiley   +1 more source

Stochastic Restricted Modified Mixed Logistic Estimator

Austrian Journal of Statistics
In this study, we introduce a new estimator named the Stochastic Restricted Modified Mixed Logistic Estimator (SRMMLE), which is specifically designed to handle multicollinearity within the framework of stochastic linear restrictions.
Kayathiri Thayaparan, Kayanan Manickavasagar , Pushpakanthie Wijekoon   +2 more
doaj   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

TIGER: A Tuning-Insensitive Approach for Optimally Estimating Gaussian Graphical Models [PDF]

, 2012
We propose a new procedure for estimating high dimensional Gaussian graphical models. Our approach is asymptotically tuning-free and non-asymptotically tuning-insensitive: it requires very few efforts to choose the tuning parameter in finite sample ...
Liu, Han, Wang, Lie
core  

On the distribution of shrinkage parameters of Liu-type estimators

Brazilian Journal of Probability and Statistics, 2009
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Alheety, M. I., Ramanathan, T. V., Gore, S. D.   +2 more
openaire   +3 more sources