Results 271 to 280 of about 107,308 (356)

Bacterial Extracellular Vesicles in the Pathogenesis and Treatment of Liver Diseases

Journal of Gastroenterology and Hepatology, EarlyView.
Liver diseases are a major global health challenge, with current treatments inadequate. This review highlights the role of bacterial extracellular vesicles in liver inflammation, fibrosis, and metabolism. We also explore these from commensals and probiotics, their protective effects, and discuss research challenges and future therapeutic potential ...
Yakun Li, Jia Li, Robin P. F. Dullaart, Han Moshage   +3 more
wiley   +1 more source

A safer cell-based yellow fever live attenuated vaccine protects mice against YFV infection. [PDF]

iScience
Guo W, Jiang T, Rao J, Zhang Z, Zhang X, Su J, Yin C, Lu M, Hu X, Shan C.   +9 more
europepmc   +1 more source

The “Reducing Inflammation for Greater Health Trial (RIGHT)” Study—Concept, Rationale, and Design

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT The Reducing Inflammation for Greater Health Trial's (RIGHT) study is a single‐center, randomized, double‐blind, placebo‐controlled trial designed to test whether clazkizumab, an interleukin‐6 (IL‐6) inhibitor, can improve or slow decline in physical, cognitive, and vascular function in older adults, when compared to a placebo.
Sebastian E. Sattui, Marnie Bertolet, Daniel E. Forman, Michelle E. Danielson, Shanshan Yao, Oscar L. Lopez, Nancy W. Glynn, Neelesh K. Nadkarni, Akira Sekikawa, Tullia C. Bruno, Toren Finkel, Anne B. Newman   +11 more
wiley   +1 more source

A live attenuated vaccine to prevent severe neonatal Escherichia coli K1 infections. [PDF]

Nat Commun
Sereme Y, Schrimp C, Faury H, Agapoff M, Lefebvre-Wloszczowski E, Chang Marchand Y, Ageron-Ardila E, Panafieu E, Blec F, Coureuil M, Frapy E, Tsatsaris V, Bonacorsi S, Skurnik D.   +13 more
europepmc   +1 more source

Gossypiboma‐associated sarcomas in five cases

Journal of Small Animal Practice, EarlyView.
Objectives To report clinical presentation, treatment and outcome of dogs and cats diagnosed with gossypiboma‐associated sarcoma. Materials and Methods Referral centres within the United Kingdom, Europe, North America and Australia were contacted to search medical records for dogs and cats with documented gossypiboma‐associated sarcoma and included if ...
G. Thomas, L. Doeven, A. Guillén, D. Brockman, E. Herbert, S. Priestnall, J. Helm, K. Shimura, M. Simpson   +8 more
wiley   +1 more source

Development of a live attenuated vaccine candidate for equid alphaherpesvirus 1 control: a step towards efficient protection. [PDF]

Front Immunol
Hu Y, Wu G, Jia Q, Zhang B, Sun W, Sa R, Zhang S, Cai W, Jarhen, Ran D, Liu J.   +10 more
europepmc   +1 more source

Narcolepsy and rapid eye movement sleep

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Since the first description of narcolepsy at the end of the 19th Century, great progress has been made. The disease is nowadays distinguished as narcolepsy type 1 and type 2. In the 1960s, the discovery of rapid eye movement sleep at sleep onset led to improved understanding of core sleep‐related disease symptoms of the disease (excessive ...
Francesco Biscarini, Lucie Barateau, Fabio Pizza, Giuseppe Plazzi, Yves Dauvilliers   +4 more
wiley   +1 more source

Immunology of CBPP: current knowledge [PDF]

, 2014
Totté, Philippe
core  

Live, Attenuated Venezuelan Equine Encephalitis Virus Vaccine (TC83) Causes Persistent Brain Infection in Mice with Non-functional αβ T-Cells

, 2017
Katherine Taylor, Olga A. Kolokoltsova, Shannon E. Ronca, Mark Estes, Slobodan Paessler   +4 more
openalex   +1 more source

Reflecting on experiences of resident redeployment during the COVID‐19 pandemic: Implications for leadership and theory beyond the crisis

Medical Education, EarlyView.
Abstract Introduction This study explored medical residents' experiences of redeployment during the COVID‐19 pandemic. With the benefit of time and reflection, this study went beyond an ‘educational deficit’ perspective on redeployment and examined these experiences to better understand enduring tensions in medical education, prepare leaders for ...
Paula Rowland, Melanie Hammond Mobilio, Meredith Giuliani, Cynthia Whitehead, Patricia Houston   +4 more
wiley   +1 more source