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Live, Attenuated Mumps-Virus Vaccine

New England Journal of Medicine, 1968
Abstract Jeryl-Lynn strain (B level) live, attenuated mumps-virus vaccine was administered to 6283 initially susceptible children and 163 adults, including 132 males. There was no evident clinical reaction to the vaccine either in adults or in children including infants.
M R, Hilleman   +3 more
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Live Attenuated Vaccine Vectors

International Journal of Technology Assessment in Health Care, 1994
AbstractSeveral different live attenuated vaccine vectors currently are under development. These vaccines are composed of living viruses or bacteria that are innocuous to the host but can replicate in host tissues and induce immune responses. The genes encoding foreign antigens can be inserted into these vectors to produce multivalent vaccines that ...
openaire   +2 more sources

Influenza Vaccination with a Live Attenuated Vaccine

AJN, American Journal of Nursing, 2009
Influenza is a highly contagious, acute respiratory illness with a long history of outbreaks dating back several centuries. Although immunization is an effective means of protection against influenza, vaccination rates have been suboptimal, especially among certain high-risk groups, including children and health care personnel.
Michele, Michael   +4 more
openaire   +2 more sources

Live Attenuated Influenza Vaccine - A review

Journal of preventive medicine and hygiene, 2011
Owing to the variability of influenza viruses, vaccine composition needs to be up-dated annually. As many variables can influence their efficacy, vaccines are still considered ?sub-optimal?. Many studies have been carried out in recent years to improve vaccines.
GASPARINI, ROBERTO   +3 more
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Live Attenuated Oral Poliovirus Vaccine

Clinical Infectious Diseases, 1984
During 1952-1954, some of the first papers were published on the attenuation of wild poliovirus for vaccine purposes. These efforts soon came to fruition , and large-scale field trials were held in many countries under a variety of conditions. Routine use of live oral poliovirus vaccines ( OPV ) was begun in many countries during the spring of 1960 ...
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Live-attenuated chikungunya virus vaccine

Cell
Although Chikungunya fever does not a have a high fatality rate (
Lisa F P, Ng, Laurent, Rénia
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Live Attenuated Varicella-Zoster Vaccine

Clinical Infectious Diseases, 1980
Varicella-zoster (VZ) virus causes two diseases, varicella and zoster. Because it was recognized that, after varicella, latent VZ virus persisted in the host and because varicella was thought to be a milde disease, there was little impetus in North America to develop a live VZ vaccine.
openaire   +2 more sources

Live Attenuated Viral Vaccines

2014
The history of vaccination using live viruses extends through several centuries and is directly intertwined with the elimination of smallpox (variola major, Plotkin and Plotkin 2004). The word vaccine comes from the Latin “vaccinus” meaning “of cows”—an adjective joining variola (smallpox) and vaccinae to form cowpox (variola vaccinae, Jenner 1798 ...
Mark S. Galinski   +3 more
openaire   +1 more source

Vaccination with Live Attenuated Measles Virus

Archives of Pediatrics & Adolescent Medicine, 1962
Introduction Isolation of the virus of measles in human tissue culture and its subsequent adaptation to growth in embryonated eggs and chick embryo cell culture by Enders and his colleagues 1-3 has led to the rapid development in the United States of vaccines suitable for use in the immunoprophylaxis of this disease.
R B, HORNICK   +2 more
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Immunization with Live Attenuated Poliovirus Vaccine

Archives of Pediatrics & Adolescent Medicine, 1961
Live attenuated poliovirus vaccine was administered to 400 newborn infants during a three-month period (October, 1959, to January, 1960). This study was designed to obtain information which might provide answers to the following questions. Would the ingestion of larger doses permit enough of the vaccine viruses regularly to pass the "acid barrier" of ...
S, KRUGMAN   +5 more
openaire   +2 more sources

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