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Live Attenuated Influenza Vaccine in Children
Seminars in Pediatric Infectious Diseases, 2006Live attenuated influenza vaccine (LAIV) offers a novel approach to influenza vaccination and is approved for healthy individuals 5 to 49 years of age. In placebo-controlled studies in children, LAIV was 73 to 93 percent efficacious, and protection lasted more than 12 months.
Christopher S, Ambrose +2 more
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Live attenuated vaccines for human use
Current Opinion in Biotechnology, 1992Live attenuated vaccines have been successfully used for the prevention of a number of viral and bacterial diseases. Several vaccine strains have been utilized recently as expression vectors for cloned heterologous antigens. Through the use of recombinant DNA technology, candidate vaccine strains and vector systems have been developed and are ...
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A live attenuated human rotavirus vaccine
Drugs of Today, 2007Rotavirus infections are the leading cause of severe gastroenteritis in young children worldwide. This review provides a summary of the development of a live oral rotavirus vaccine, Rotarix (GlaxoSmithKline, Rixensart, Belgium) developed from a single protective G1P[8] human strain.
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Live Attenuated Human Rotavirus Vaccine, Rotarix™
Seminars in Pediatric Infectious Diseases, 2006Rotavirus infections are the leading cause of severe gastroenteritis in young children worldwide. Recently two new rotavirus vaccines have entered the world market. This review provides a summary of the rationale, development, and evaluation of one of these vaccines, Rotarix.
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Live Attenuated Vaccines for Pandemic Influenza
2009In this chapter, we will review the development of and clinical experience with the currently licensed seasonal live attenuated influenza vaccines (LAIV) and preclinical studies of H5, H7, and H9 live attenuated pandemic influenza vaccine candidates. Vectored vaccine approaches will not be reviewed in this chapter.
Grace L, Chen, Kanta, Subbarao
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Designing spatial and temporal control of vaccine responses
Nature Reviews Materials, 2021Shih Hao Ou, Wei Luo, Bali Pulendran
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COVID-19 vaccine guidance for patients with cancer participating in oncology clinical trials
Nature Reviews Clinical Oncology, 2021Aakash Desai +2 more
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[Influenza live attenuated vaccine].
Nihon rinsho. Japanese journal of clinical medicine, 2001Inactivated influenza vaccine has been widely used; however, its effectiveness is not always perfect. To create a much better vaccine, live vaccines have been extensively investigated. Among several candidate live vaccines, cold-adapted(Ca) vaccine is the only promising candidate. According to clinical studies recently conducted in the U.S., Ca vaccine
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Emerging concepts in the science of vaccine adjuvants
Nature Reviews Drug Discovery, 2021Bali Pulendran, Prabhu S Arunachalam
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Human papillomavirus vaccination 2020 guideline update: American Cancer Society guideline adaptation
Ca-A Cancer Journal for Clinicians, 2020Robert A Smith
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