PROTAC vaccine: A new way to live attenuated vaccines [PDF]
Clinical and Translational Medicine, 2022 Zhen Li +6 more
doaj +4 more sources
Rational Design of Live-Attenuated Vaccines against Herpes Simplex Viruses [PDF]
Viruses, 2021 Diseases caused by human herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) affect millions of people worldwide and range from fatal encephalitis in neonates and herpes keratitis to orofacial and genital herpes, among other manifestations.
Brent A. Stanfield +3 more
doaj +2 more sources
Biomarkers of safety and immune protection for genetically modified live attenuated Leishmania vaccines against visceral leishmaniasis-Discovery and implications [PDF]
Frontiers in Immunology, 2014 Despite intense efforts there is no safe and efficacious vaccine against visceral leishmaniasis, which is fatal and endemic in many tropical countries. A major shortcoming in the vaccine development against blood borne parasitic agents such as Leishmania
Sreenivas eGannavaram +5 more
doaj +9 more sources
Engineering live attenuated vaccines: Old dogs learning new tricks [PDF]
Journal of Translational Autoimmunity, 2023 Autoimmune diseases such as rheumatoid arthritis and type 1 diabetes are increasingly common global problems. Concerns about increases in the prevalence of such diseases and the limited efficacy of conventional treatment regimens necessitates new ...
Julia Plocica +7 more
doaj +2 more sources
Live-Attenuated Vaccines in Pediatric Solid Organ Transplant [PDF]
VaccinesMeasles, mumps, rubella (MMR), and varicella incidence rates have increased due to the delayed vaccination schedules of children secondary to the COVID-19 pandemic. Decreased herd immunity creates a risk for immunocompetent children and immunocompromised
Christopher Hartley +3 more
doaj +2 more sources
Viral Live‐Attenuated Vaccines (LAVs): Past and Future Directions [PDF]
Advanced ScienceViral infections continue to pose a significant threat to the health of both humans and animals. Currently, live attenuated vaccines (LAVs) remain the most efficacious and widely utilized tool for combating viral infections. Conventional LAVs involve the
Yan‐Dong Tang +3 more
doaj +2 more sources
Current efforts towards safe and effective live attenuated vaccines against African swine fever: challenges and prospects. [PDF]
Infect Dis Poverty, 2021 Wang T, Luo R, Sun Y, Qiu HJ.
europepmc +3 more sources
LIVE ATTENUATED VACCINES FOR THE IMMUNOPROPHYLAXIS
Инфекция и иммунитет, 2017 The review focuses on the history of the production of live antiviral vaccines and their use for the prevention of infectious diseases. It was noted that before the beginning of the 20th century, only three live vaccines were developed and put into ...
O. A. Shamsutdinova
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Live Attenuated Vaccines against Tuberculosis: Targeting the Disruption of Genes Encoding the Secretory Proteins of Mycobacteria [PDF]
VaccinesTuberculosis (TB), a chronic infectious disease affecting humans, causes over 1.3 million deaths per year throughout the world. The current preventive vaccine BCG provides protection against childhood TB, but it fails to protect against pulmonary TB ...
Raja Veerapandian +3 more
doaj +2 more sources
Preclinical and clinical experience with dupilumab on the correlates of live attenuated vaccines. [PDF]
J Allergy Clin Immunol Glob, 2022 Wechsler ME +15 more
europepmc +2 more sources