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Live attenuated vaccines for tuberculosis [PDF]
The Biochemist, 2021 Tuberculosis (TB) is a leading cause of infectious death worldwide. TB is caused by the bacterium Mycobacterium tuberculosis (Mtb) and transmission happens via inhalation of droplets and aerosols coughed by an individual with active disease. There are about 10 million cases of active TB annually, and it is estimated that approximately 2 billion people ...
Kupz, Andreas
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Live attenuated polio vaccine and the risk of intussusception [PDF]
British Journal of Clinical Pharmacology, 2001 Aims Since suspicion has been raised that administration of an oral live attenuated rotavirus vaccine may increase the risk of intussusception in young children, there has been concern about the possible effects of oral polio vaccine. The aim of the study was to evaluate the relationship between oral attenuated polio vaccine and intussusception in ...
Hershel Jick +2 more
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Quality control procedure for Coccidial vaccines versus different routes of immunization [PDF]
Veterinary World, 2022 Background and Aim: Coccidiosis is an enteric infection caused by a protozoon (Eimeria tenella). Coccidiosis is known to have a negative impact on the economy. Coccidiosis is controlled using anticoccidial drugs, antibiotics, and vaccines.
Arwa Elnaggar, Hala Mahmoud, Sahar Saber
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PROTAC vaccine: A new way to live attenuated vaccines
Clinical and Translational Medicine, 2022 Zhen Li +6 more
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Different Types of Vaccines against Pestiviral Infections: “Barriers” for “Pestis”
Viruses, 2022 The genus Pestivirus of the family Flaviviridae mainly comprises classical swine fever virus (CSFV), bovine viral diarrhea virus 1 (BVDV-1), BVDV-2, border disease virus (BDV), and multiple new pestivirus species such as atypical porcine pestivirus (APPV)
Mengqi Yuan +6 more
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Perspectives of Next-Generation Live-Attenuated Rift Valley Fever Vaccines for Animal and Human Use
Vaccines, 2023 Live-attenuated Rift Valley fever (RVF) vaccines transiently replicate in the vaccinated host, thereby effectively initiating an innate and adaptive immune response.
Paul J. Wichgers Schreur +4 more
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Rational Design of Live-Attenuated Vaccines against Herpes Simplex Viruses
Viruses, 2021 Diseases caused by human herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) affect millions of people worldwide and range from fatal encephalitis in neonates and herpes keratitis to orofacial and genital herpes, among other manifestations.
Brent A. Stanfield +3 more
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Rational Development of Live-Attenuated Zika Virus Vaccines
Pathogens, 2023 Zika virus (ZIKV), a re-emerging mosquito-borne flavivirus, has caused outbreaks in Africa, Asia, the Pacific, and, more recently, in the Americas. ZIKV has been associated with the neurological autoimmune disorder Guillain–Barre syndrome in adults and ...
Awadalkareem Adam +2 more
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Improvements to the live-attenuated Newcastle disease virus vaccine using Carbopol® 940 as a stabilizer [PDF]
Veterinary World, 2020 Background and Aim: One strategy that can be used to stabilize vaccines is to convert them into a dry powder. This can protect the integrity of the active ingredients as well as vaccine antigenicity during manufacture, storage, and transport.
Mahmoud Mohamed Abd El-Moneam +3 more
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Live attenuated intranasal influenza vaccine [PDF]
Human Vaccines & Immunotherapeutics, 2012 Annual vaccination is the most effective means of preventing and controlling influenza epidemics, and the traditional trivalent inactivated vaccine (TIV) is by far the most widely used. Unfortunately, it has a number of limitations, the most important of which is its poor immunogenicity in younger children and the elderly, the populations at greatest ...
Esposito, Susanna Maria Roberta +5 more
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