Vaccines against toxoplasma gondii : challenges and opportunities [PDF]
, 2009 Development of vaccines against Toxoplasma gondii infection in humans is of high priority, given the high burden of disease in some areas of the world like South America, and the lack of effective drugs with few adverse effects.
Jongert, Erik +4 more
core +4 more sources
Rational Development of Live-Attenuated Zika Virus Vaccines
Pathogens, 2023 Zika virus (ZIKV), a re-emerging mosquito-borne flavivirus, has caused outbreaks in Africa, Asia, the Pacific, and, more recently, in the Americas. ZIKV has been associated with the neurological autoimmune disorder Guillain–Barre syndrome in adults and ...
Awadalkareem Adam +2 more
doaj +1 more source
Developing Next-Generation Live Attenuated Vaccines for Porcine Epidemic Diarrhea Using Reverse Genetic Techniques. [PDF]
Vaccines (Basel)Porcine epidemic diarrhea virus (PEDV) is the etiology of porcine epidemic diarrhea (PED), a highly contagious digestive disease in pigs and especially in neonatal piglets, in which a mortality rate of up to 100% will be induced. Immunizing pregnant sows
Yu R, Dong S, Chen B, Si F, Li C.
europepmc +2 more sources
Live Viral Vaccine Neurovirulence Screening: Current and Future Models
Vaccines, 2021 Live viral vaccines are one of the most successful methods for controlling viral infections but require strong evidence to indicate that they are properly attenuated.
Corey May Fulton, Wendy J. Bailey
doaj +1 more source
Codon pair bias and viral vaccine design [PDF]
, 2015 The authors acknowledge the long term support of the Wellcome Trust and the Biotechnology and Biological Sciences Research Council.Live attenuated vaccines (LAVs) have prevented morbidity and mortality against a number of important viral diseases (such ...
Tulloch, Fiona Ashley +3 more
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Parenteral vaccination of mammalian livestock with Newcastle disease virus-based vector vaccines offers optimal efficacy and safety [PDF]
, 2011 Newcastle disease virus (NDV) is an avian virus that is being evaluated as a vaccine vector for the delivery of foreign genes in mammals. The use of NDV as a vaccine vector in these species offers two major advantages.
Adriaan F.G. Antonis +7 more
core +1 more source
Safety of measles-containing vaccines in post-marketing surveillance in Anhui, China. [PDF]
PLoS ONE, 2017 The safety of measles vaccination is of great interest and importance to public health practice and the general society. We have analyzed the adverse events following immunization (AEFIs) of currently used measles-containing vaccines (including live ...
Fan-Ya Meng +7 more
doaj +1 more source
Evaluate Risk Analysis of Measurement Uncertainty (MU) of Different Methods Applied for Veterinary Vaccines Evaluation [PDF]
Journal of Applied Veterinary Sciences, 2022 Veterinary Serum and Vaccine Research Institute (VSVRI ) objected to producing highly efficient vaccines from reference or local isolates according to the international specifications for protecting animals and poultry against different diseases and ...
Hala Elsawy +5 more
doaj +1 more source
Improvements to the live-attenuated Newcastle disease virus vaccine using Carbopol® 940 as a stabilizer [PDF]
Veterinary World, 2020 Background and Aim: One strategy that can be used to stabilize vaccines is to convert them into a dry powder. This can protect the integrity of the active ingredients as well as vaccine antigenicity during manufacture, storage, and transport.
Mahmoud Mohamed Abd El-Moneam +3 more
doaj +1 more source
Development of Streptococcus pneumoniae Vaccines Using Live Vectors [PDF]
, 2015 : Streptococcus pneumoniae still causes severe morbidity and mortality worldwide, especially in young children and the elderly. Much effort has been dedicated to developing protein-based universal vaccines to conquer the current shortcomings of capsular ...
core +1 more source