A live-attenuated SARS-CoV-2 vaccine candidate with accessory protein deletions
Nature Communications, 2022 A live-attenuated COVID vaccine could enrich the current vaccine portfolio. Here, Liu et al. engineer a live-attenuated SARS-CoV-2 vaccine candidate by deleting four viral accessory genes and show immunogenicity and protection in mice and hamsters.
Yang Liu +18 more
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Field Trial Demonstrates Superiority of a Live Attenuated Vaccine for Integrated Control of Mycoplasmal pneumonia of Swine and Improved Production Performance in Commercial Swine Farms [PDF]
AnimalsA field trial was conducted on a single commercial swine farm to compare the integrated control efficacy of an inactivated vaccine and a live attenuated vaccine against mycoplasmal pneumonia of swine (MPS).
Changhua Lin +5 more
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Cost-Effectiveness Analysis of Herpes Zoster Vaccination in a Chinese Population: Recombinant Subunit Vaccine versus Live Attenuated Vaccine [PDF]
VaccinesBackground: Currently, the recombinant subunit vaccine and live attenuated vaccine in the prevention of herpes zoster are approved for marketing in China.
Jiaqi Wang +5 more
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Evaluation of the Safety Profile of the ASFV Vaccine Candidate ASFV-G-ΔI177L
Viruses, 2022 African swine fever (ASF) is the cause of a recent pandemic that is posing a threat to much of the world swine production. The etiological agent, ASF virus (ASFV), infects domestic and wild swine, producing a variety of clinical presentations depending ...
Xuan Hanh Tran +10 more
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Rational Development of Live-Attenuated Zika Virus Vaccines
Pathogens, 2023 Zika virus (ZIKV), a re-emerging mosquito-borne flavivirus, has caused outbreaks in Africa, Asia, the Pacific, and, more recently, in the Americas. ZIKV has been associated with the neurological autoimmune disorder Guillain–Barre syndrome in adults and ...
Awadalkareem Adam +2 more
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H5N1 vaccine-specific B cell responses in ferrets primed with live attenuated seasonal influenza vaccines. [PDF]
PLoS ONE, 2009 Live attenuated influenza H5N1 vaccines have been produced and evaluated in mice and ferrets that were never exposed to influenza A virus infection (Suguitan et al., Plos Medicine, e360:1541, 2006).
Xing Cheng +7 more
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Safety of measles-containing vaccines in post-marketing surveillance in Anhui, China. [PDF]
PLoS ONE, 2017 The safety of measles vaccination is of great interest and importance to public health practice and the general society. We have analyzed the adverse events following immunization (AEFIs) of currently used measles-containing vaccines (including live ...
Fan-Ya Meng +7 more
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Summary of the Current Status of African Swine Fever Vaccine Development in China
Vaccines, 2023 African swine fever (ASF) is a highly lethal and contagious disease of domestic pigs and wild boars. There is still no credible commercially available vaccine.
Naijun Han +5 more
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Frontiers in Microbiology, 2022 In the second half of 2021, a highly pathogenic case occurred in a mixed chicken and duck family farm in Guangdong, China. After the duck flocks were immunized with live attenuated duck enteritis virus vaccine (live attenuated DEV vaccine), the chickens ...
Jie Kong +38 more
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Improvements to the live-attenuated Newcastle disease virus vaccine using Carbopol® 940 as a stabilizer [PDF]
Veterinary World, 2020 Background and Aim: One strategy that can be used to stabilize vaccines is to convert them into a dry powder. This can protect the integrity of the active ingredients as well as vaccine antigenicity during manufacture, storage, and transport.
Mahmoud Mohamed Abd El-Moneam +3 more
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