Results 31 to 40 of about 1,671,583 (304)

Intranasal delivery of a rationally attenuated SARS-CoV-2 is immunogenic and protective in Syrian hamsters

Nature Communications, 2022
Examples of effective live attenuated viral vaccines include the measles, mumps and rubella vaccine, as well as the chickenpox vaccine. In this work, the authors engineer a live attenuated SARS-CoV-2 virus that demonstrates attenuation in numerous in ...
Shufeng Liu, Charles B. Stauft, Prabhuanand Selvaraj, Prabha Chandrasekaran, Felice D’Agnillo, Chao-Kai Chou, Wells W. Wu, Christopher Z. Lien, Clement A. Meseda, Cyntia L. Pedro, Matthew F. Starost, Jerry P. Weir, Tony T. Wang   +12 more
doaj   +1 more source

Five-year antibody persistence in children after one dose of inactivated or live attenuated hepatitis A vaccine

Human Vaccines & Immunotherapeutics, 2017
In China, both inactivated hepatitis A (HA) vaccine and live attenuated HA vaccine are available. We conducted a trial to evaluate 5-year immune persistence induced by one dose of inactivated or live attenuated HA vaccines in children.
Zhilun Zhang, Xiangjun Zhu, Yuansheng Hu, Miao Liang, Jin Sun, Yufei Song, Qi Yang, Haiquan Ji, Gang Zeng, Lifei Song, Jiangting Chen   +10 more
doaj   +1 more source

Inhibitors of the interferon response enhance virus replication in vitro. [PDF]

, 2014
This work was supported by the University of St Andrews (CSA, CES) and the Wellcome Trust (grant 087751/A/08/Z) (RER).Virus replication efficiency is influenced by two conflicting factors, kinetics of the cellular interferon (IFN) response and induction ...
Richard E. Randall, Catherine S. Adamson, Catherine S Adamson, Claire E Stewart, Richard E Randall, Adamson, Catherine S, Stewart, Claire Emma, Randall, Richard Edward, Claire E. Stewart   +8 more
core   +1 more source

Protective efficacy and DIVA potential of a

Poultry Science
Salmonella Enteritidis poses a significant threat to poultry health and production, leading to substantial economic losses worldwide. Transmission through contaminated poultry products poses a continuous risk to public health.
Yanyu Ruan, Xilong Kang, Zeyun Lin, Tianlong Sun, Zhiming Pan, Xinwei Wang, Tingting Pan, Yimeng Zhao, Hongqin Song   +8 more
doaj   +1 more source

Preparation Of Live Attenuated Vaccine Against Strangles

The Iraqi Journal of Veterinary Medicine, 2007
Live attenuated vaccine of Strept. Equi was prepared by culturing the bacterium in increasing concentration of acriflavin and the vaccine was given by installation in the nose of rabbits.
M. M. Kaisium
doaj   +1 more source

Research note: Comparison of live attenuated and non-attenuated Eimeria vaccines on safety following overdose administration using the European pharmacopoeia monograph model

Poultry Science
Live non-attenuated and attenuated coccidiosis vaccines are available and induce a solid immune response to Eimeria spp. However, knowledge regarding the safety of live non-attenuated Eimeria vaccines is still limited.
Marc Pagès, Andreu Albó, Gregori Bech-Sàbat, Roser Morató, Joan Molist-Badiola, Martina Dardi   +5 more
doaj   +1 more source

An escherichia coli vaccine co-expressing listeriolysin-O and tumour antigen in cancer immunotherapy and the mechanisms of immune regulation [PDF]

, 2009
PhDSome recombinant bacterial strains have been shown to be very efficient in experimental therapies against cancer in rodent models. Amongst them is an E. coli that expresses the Listeriolysin-O protein (LLO) and a model tumour antigen ovalbumin (OVA)
Dai, Ming-Shen
core   +4 more sources

Single-Dose Immunogenic DNA Vaccines Coding for Live-Attenuated Alpha- and Flaviviruses

Viruses
Single-dose, immunogenic DNA (iDNA) vaccines coding for whole live-attenuated viruses are reviewed. This platform, sometimes called immunization DNA, has been used for vaccine development for flavi- and alphaviruses.
Peter Pushko, Igor S. Lukashevich, Dylan M. Johnson, Irina Tretyakova   +3 more
doaj   +1 more source

A 5-year follow-up of antibody response in children vaccinated with single dose of live attenuated SA14-14-2 Japanese encephalitis vaccine: immunogenicity and anamnestic responses

, 2008
Out of 98 subjects who had participated in the 2000 JE vaccination campaign, 69 people were enrolled in the tests of 2004 and 2005 for the evaluation of long term immune response of a single dose of live attenuated SA14-14-2 JE vaccine.
오희철
core   +1 more source

Codon pair bias and viral vaccine design [PDF]

, 2015
The authors acknowledge the long term support of the Wellcome Trust and the Biotechnology and Biological Sciences Research Council.Live attenuated vaccines (LAVs) have prevented morbidity and mortality against a number of important viral diseases (such ...
Tulloch, Fiona Ashley, Ryan, Martin Denis, Pathania, Uday Singh, Luke, Garry Alec   +3 more
core   +1 more source