Results 51 to 60 of about 1,671,583 (304)

Identification of attenuation markers of a Theileria lestoquardi cell line to be used for the development of live vaccine against malignant ovine theileriosis [PDF]

, 2010
Theileria lestoquardi is a tick-borne protozoan parasite and highly pathogenic for sheep. The disease caused by the pathogen is known as malignant ovine theileriosis (MOT) and is transmitted by Hyalomma ticks.
Mousa, Awadia Mohamed Ali Mohamed
core   +1 more source

Vaccination coverage and its determinants of live attenuated hepatitis A vaccine among children aged 24–59 months in 20 rural counties of 10 provinces of China in 2016

Human Vaccines & Immunotherapeutics, 2020
Objective To understand one single dose coverage of live attenuated hepatitis A vaccine and its determinants among children aged 24–59 months in 20 rural counties of 10 provinces of China in 2016.
Xiaoli Liu, Chenlu Yang, Xueqi Qu, Nan Li, Xiaona Huang, Yuning Yang, Yiming Zhao, Yan Wang, Hong Zhou   +8 more
doaj   +1 more source

Reduced immunogenicity of a live Salmonella enterica serovar Typhimurium vaccine in aged mice

Frontiers in Immunology, 2023
IntroductionNon-typhoidal Salmonella (NTS) is responsible for a high burden of foodborne infections and deaths worldwide. In the United States, NTS infections are the leading cause of hospitalizations and deaths due to foodborne illnesses, and older ...
Jessica C. Allen, Jessica C. Allen, Franklin R. Toapanta, Franklin R. Toapanta, Scott M. Baliban, Scott M. Baliban, Marcelo B. Sztein, Marcelo B. Sztein, Marcelo B. Sztein, Sharon M. Tennant, Sharon M. Tennant   +10 more
doaj   +1 more source

Brucellosis: The case for live, attenuated vaccines [PDF]

Vaccine, 2009
The successful control of animal brucellosis and associated reduction in human exposure has limited the development of human brucellosis vaccines. However, the potential use of Brucella in bioterrorism or biowarfare suggests that direct intervention strategies are warranted.
Thomas A, Ficht, Melissa M, Kahl-McDonagh, Angela M, Arenas-Gamboa, Allison C, Rice-Ficht   +3 more
openaire   +2 more sources

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Live attenuated intranasal influenza vaccine [PDF]

Human Vaccines & Immunotherapeutics, 2012
Annual vaccination is the most effective means of preventing and controlling influenza epidemics, and the traditional trivalent inactivated vaccine (TIV) is by far the most widely used. Unfortunately, it has a number of limitations, the most important of which is its poor immunogenicity in younger children and the elderly, the populations at greatest ...
Esposito, Susanna Maria Roberta, V. Montinaro, E. Groppali, R. Tenconi, M. Semino, N. Principi   +5 more
openaire   +7 more sources

Signals and trends of Guillain-Barré syndrome after the introduction of live-attenuated vaccines for influenza in the US and South Korean adverse event reporting systems

, 2020
Background: With the advent of live-attenuated, quadrivalent, and cell-cultured vaccines for influenza, there have been discussions on the safety of these vaccines compared to conventional vaccines (such as inactivated, trivalent, and egg-cultured ...

core   +1 more source

Aptamer‐Engineered Liposomal Platform Enables in Situ cDC1 Vaccination to Potentiate Immunotherapy in Prostate Cancer

Advanced Science, EarlyView.
Prostate cancer is immunologically ‘cold’, with scarce, dysfunctional type 1 conventional dendritic cells (cDC1s) that limit T cell priming. We introduce an aptamer‐targeted liposomedelivering FMS‐like tyrosine kinase 3 ligand (Flt3L) and chlorin e6 (Ce6). Ultrasound induces antigen release and cDC1s recruitment, creating an in situ cDC1 vaccine.
Jiayi Wang, Xuan Wang, Xinfeng Dai, Linxin Tian, Wencheng Shen, Xueliang Liu, Wei Xue, Jiahua Pan, Yu Yang   +8 more
wiley   +1 more source

Liposomal Delivery of the RNA Genome of a Live-Attenuated Chikungunya Virus Vaccine Candidate Provides Local, but Not Systemic Protection After One Dose

Frontiers in Immunology, 2020
Chikungunya virus (CHIKV) is the causative pathogen of chikungunya fever, a mosquito-borne viral disease causing highly debilitating arthralgia that can persist for months and progress to chronic arthritis.
Eranga Abeyratne, Eranga Abeyratne, Kothila Tharmarajah, Kothila Tharmarajah, Joseph R. Freitas, Joseph R. Freitas, Helen Mostafavi, Helen Mostafavi, Suresh Mahalingam, Suresh Mahalingam, Ali Zaid, Ali Zaid, Mehfuz Zaman, Adam Taylor, Adam Taylor   +14 more
doaj   +1 more source

Administration of live-attenuated vaccine of Vibrio harveyi to improve survival of gnotobiotic brine shrimp (Artemia salina) model against multipleVibrio infection [PDF]

, 2019
Newly developed live-attenuated protease derivative from pathogenic Vibrio harveyis train Vh1 as a live vaccine to against Vibriosis of aquatic animals. In the current study, we used the gnotobiotic A.
Md Yasin, Ina Salwany, Al-saari, Nurhidayu, Chin, Yong Kit, Mohd-Aris, Aslizah, Mohd Aris, Aslizah, Chin, Y. K., Zamri-Saad, Mohd, Saad, Mohd Zamri, Md Yasinb, Ina Salwany   +8 more
core   +1 more source