Results 141 to 150 of about 41,266 (261)

Varicella and Herpes zoster vaccines: from live attenuated vaccines to genetically engineered products

open access: yesБиопрепараты: Профилактика, диагностика, лечение
INTRODUCTION. Varicella zoster virus remains a serious threat to public health and is a sig­nificant burden on the health system due to treatment costs. Vaccination coverage against varicella zoster (VZ) and herpes zoster (HZ) remains low for a number of
A. V. Zotova, O. A. Svitich
doaj   +1 more source

Harnessing nanomaterials to precisely regulate the immunosuppressive tumor microenvironment for enhanced immunotherapy

open access: yesBMEMat, EarlyView.
The immunosuppressive tumor microenvironment, characterized by hypoxia, redox imbalance, elevated interstitial fluid pressure, and acidity, was comprehensively elucidated. This review discussed the etiology and consequences of the characteristics of the immunosuppressive tumor microenvironment, and analyzed the recent advancements in nanomaterials for ...
Wen Zhang   +7 more
wiley   +1 more source

Nanomaterials‐mediated glycolysis rewriting to potentiate tumor immunotherapy

open access: yesBMEMat, EarlyView.
This review systematically summarizes cutting‐edge advances in glycolysis‐rewiring nanomedicines, emphasizing their mechanisms in reversing immunosuppression and reinvigorating antitumor immune responses. Challenges in clinical translation and future directions for designing multifunctional metabolic‐immune modulators are also critically discussed ...
Zilin Ma   +9 more
wiley   +1 more source

Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases

open access: yesBMEMat, EarlyView.
This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou   +6 more
wiley   +1 more source

Reprogramming tumor immune microenvironment by ultrasound‐responsive nanoplatforms for enhanced cancer immunotherapy

open access: yesBMEMat, EarlyView.
Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao   +4 more
wiley   +1 more source

Attenuated African swine fever viruses and the live vaccine candidates: a comprehensive review

open access: yesMicrobiology Spectrum
The African swine fever virus (ASFV) is spreading worldwide and causing huge economic losses to the global pig industry. The ASFV genome is 170–193 kb in length, contains approximately 150 open reading frames, and encodes more than 200 proteins, most of ...
Jiaqi Fan   +4 more
doaj   +1 more source

Optimizing sterile filtration of nanoemulsions through proper choice of prefilter properties

open access: yesBiotechnology Progress, EarlyView.
Abstract Nanoemulsions, with droplet sizes between 20 and 200 nm, have emerged as a promising vaccine adjuvant and drug delivery system, enhancing the solubility of hydrophobic drugs for diverse applications. Sterile filtration of nanoemulsions is particularly challenging due to the similar size between the nanodroplets and the 0.2 μm nominal pore size
Shreya Kapila   +4 more
wiley   +1 more source

PROTAC vaccine: A new way to live attenuated vaccines

open access: yesClinical and Translational Medicine, 2022
Zhen Li   +6 more
doaj   +1 more source

The Effectiveness of Interventions Addressing Conspiracy Beliefs: A Meta‐Analysis

open access: yesEuropean Journal of Social Psychology, EarlyView.
ABSTRACT Reducing conspiracy beliefs through effective interventions may help mitigate potential harmful consequences, such as vaccine hesitancy and prejudice. Therefore, a systematic literature search was conducted in Web of Science, PsycINFO, and Google Scholar for experiments testing interventions that could potentially reduce conspiracy beliefs ...
Lukasz Stasielowicz
wiley   +1 more source

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