Results 171 to 180 of about 53,240 (309)

Beyond PD‐1/PD‐L1: New Immune Checkpoints and Therapeutic Combinations in Cancer Immunotherapy

open access: yesMedicine Bulletin, EarlyView.
ABSTRACT Recently, immune checkpoint inhibitors (ICIs), particularly PD‐1/PD‐L1 and CTLA‐4 inhibitors, have revolutionized cancer treatment, significantly improving survival rates for various malignancies. However, ICI therapies targeting single checkpoints on T cells still face numerous challenges, such as low response rates and post‐treatment ...
Yangyang Li, Zizhen Kang, Yanyun Du
wiley   +1 more source

Emerging Therapeutic Strategies in Anti‐Aging Medicine: A Comprehensive Review

open access: yesMedicine Bulletin, EarlyView.
ABSTRACT Aging is orchestrated by interconnected hallmarks such as genomic instability, mitochondrial dysfunction, cellular senescence, and disrupted intercellular communication, which collectively drive chronic disease progression. Recent advances have expanded therapeutic opportunities to include pharmacological agents, gene and epigenome editing ...
Yundong Peng   +8 more
wiley   +1 more source

Prospective study of live attenuated vaccines for patients receiving immunosuppressive agents. [PDF]

open access: yesPLoS One, 2020
Kamei K   +8 more
europepmc   +1 more source

Chimeric Hemagglutinin-Based Live-Attenuated Vaccines Confer Durable Protective Immunity against Influenza A Viruses in a Preclinical Ferret Model. [PDF]

open access: yesVaccines (Basel), 2021
Liu WC   +10 more
europepmc   +1 more source

Author response: A live attenuated-vaccine model confers cross-protective immunity against different species of the Leptospira genus

open access: gold, 2020
Elsio A. Wunder   +12 more
openalex   +1 more source

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