Results 171 to 180 of about 43,630 (288)

Development of a Promising Bivalent Vaccine Against Klebsiella pneumoniae Based on Glycoengineered GMMA (geGMMA)

open access: yesExploration, EarlyView.
Multidrug‐resistant Klebsiella pneumoniae poses a significant threat as a nosocomial pathogen, with no current licensed vaccines available. This study used a mutant E. coli strain expressing exogenous polysaccharides (from K. pneumoniae) to establish glycoengineered generalized modules for membrane antigens (geGMMA) vaccine platform, which demonstrated
Jingqin Ye   +13 more
wiley   +1 more source

Three Amino Acid Substitutions in the L Protein of the Human Parainfluenza Virus Type 3 cp 45 Live Attenuated Vaccine Candidate Contribute to Its Temperature-Sensitive and Attenuation Phenotypes [PDF]

open access: bronze, 1998
Mario H. Skiadopoulos   +7 more
openalex   +1 more source

Extracellular Vesicle‐Based mRNA Therapeutics and Vaccines

open access: yesExploration, EarlyView.
This review provides a comprehensive analysis of recent advancements in extracellular vesicle (EV)‐based messenger RNA (mRNA) applications for therapeutics and vaccines. It systematically outlines strategies for mRNA encapsulation within EVs and elucidates the challenges associated with this technology, offering insights into future research directions
Qi Li   +6 more
wiley   +1 more source

Reversion to neurovirulence of the live-attenuated Sabin type 3 oral pollovirus vaccine

open access: green, 1984
Alan J. Cann   +6 more
openalex   +2 more sources

A Multifaceted Review on Neodiosmin In Planta Distribution, (Bio)synthesis, Food and Health Effects

open access: yesFuture Postharvest and Food, EarlyView.
ABSTRACT Neodiosmin (NEO) is a major glycosylated flavone that is derived from the bitter flavanone neo‐hesperidin in citrus fruits including orange, lime, and lemon. One of the most important features of NEO is that it exerts a notable debittering effect on plant flavonoids justifying its wide use as a food additive.
Yuxuan Zhao   +4 more
wiley   +1 more source

AAV‐Based Intracerebral Administration of BDNF Promotes Myelin Repair and Cognitive Improvement After Cuprizone‐Induced Demyelination

open access: yesGlia, EarlyView.
AAV‐BDNF improves cognitive performance after cuprizone‐induced de‐myelination. BDNF promotes OPC maturation and enhances remyelination in the corpus callosum. Mitochondrial integrity is preserved through reduced swelling and improved morphology. ABSTRACT Multiple sclerosis (MS) is a chronic neurological disorder involving immune‐mediated demyelination
Yousra El Ouaamari   +14 more
wiley   +1 more source

Phase 2 Clinical Trial of AttenuatedSalmonella entericaSerovar Typhi Oral Live Vector Vaccine CVD 908-htrAin U.S. Volunteers [PDF]

open access: green, 2000
Carol O. Tacket   +13 more
openalex   +1 more source

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