Results 221 to 230 of about 91,730 (350)

Lipid Nanoparticles Delivering ClpP‐mRNA Suppress Pyroptosis and Senescence in Intervertebral Disc Degeneration via mTOR/BNIP3‐Activated Mitophagy

Rare Metals, EarlyView.
ABSTRACT Intervertebral disc degeneration (IDD) is a predominant cause of low back pain, significantly impacting quality of life. Mitochondrial fitness is essential in the progression of IDD, as it regulates cellular senescence and pyroptosis. This study investigates the role of mitochondrial caseinolytic protease P (ClpP) in alleviating senescence and
Kun Wang, Zhiqiang Wang, Tong Zhang, Shicheng Qiu, Guang Yang, Yanzheng Gao, Xiaofeng Lian, Xin Peng   +7 more
wiley   +1 more source

Reduced secretory antibody response to live attenuated measles and poliovirus vaccines in malnourished children. [PDF]

, 1975
R. K. Chandra
openalex   +1 more source

Reply to “Squamous Cell Carcinoma in Transporter Associated With Antigen Processing Deficiency”

JEADV Clinical Practice, EarlyView.
Aurora Fernández Galván
wiley   +1 more source

From Membrane Composition to Antimicrobial Strategies: Experimental and Computational Approaches to AMP Design and Selectivity

Small, EarlyView.
Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti, Marius F.W. Trollmann, Christina Wichmann, Thomas Gutsmann, Christian Eggeling, Rainer A. Böckmann   +5 more
wiley   +1 more source

A goatpox but not sheeppox heterologous live attenuated vaccines provide complete protection against lumpy skin disease in cattle under experimental conditions. [PDF]

Sci Rep
Haegeman A, Philips W, Mostin L, De Leeuw I, Van Campe W, Saegerman C, De Clercq K, De Regge N.   +7 more
europepmc   +1 more source

Genome sequences of the 15 bluetongue virus vaccine strains incorporated in the South African live-attenuated vaccine

Tendai A. M. Mlingo, Natasha Beeton-Kempen, Mulalo Bethuel Nthangeni, Jacques Theron, Nobalanda B. Mokoena   +4 more
openalex   +1 more source

Squamous Cell Carcinoma in Transporter Associated With Antigen Processing Deficiency

JEADV Clinical Practice, EarlyView.
Jacques Zimmer
wiley   +1 more source

Regulatory T Cells and Nanomaterials: Dual Perspectives in Therapeutics and Immunomodulation

Small Science, EarlyView.
Tregs control immune tolerance but can also enable tumor escape. Nanomaterials can now expand or stabilize Tregs to treat autoimmunity and support transplantation or conversely disrupt tumor Tregs to boost antitumor immunity. We also discuss unintended Treg modulation by nanoparticles, safety and manufacturing challenges, and future translational ...
Yiyin Chen, Haibo Huang, Xiang Wang, Xinghao Yu, Ziyan Huang, Zhou Jin, Chen Chen, Yan Chen, Bruce R. Blazar, Yang Xu, Yunjie Lu   +10 more
wiley   +1 more source

Hemagglutination-Inhibition Antibodies and Protection against Influenza Elicited by Inactivated and Live Attenuated Vaccines in Children. [PDF]

J Infect Dis
Yegorov S, Brewer A, Cyr L, Ward BJ, Pullenayegum E, Miller MS, Loeb M.   +6 more
europepmc   +1 more source

Immunoinformatics Identification of the Conserved and Cross-Reactive T-Cell Epitopes of SARS-CoV-2 with Human Common Cold Coronaviruses, SARS-CoV, MERS-CoV and Live Attenuated Vaccines Presented by HLA Alleles of Indonesian Population. [PDF]

Viruses, 2022
Gustiananda M, Julietta V, Hermawan A, Febriana GG, Hermantara R, Kristiani L, Sidhartha E, Sutejo R, Agustriawan D, Andarini S, Parikesit AA.   +10 more
europepmc   +1 more source