Results 221 to 230 of about 43,630 (288)

Impaired Cytokine Secretion Contributes to Age‐Dependent Immune Dysfunction in SARS Coronavirus Response and Is Restored by Young CD11b‐Positive Cell Transfer

Aging Cell, EarlyView.
Aged CD11b+ cells exhibit impaired IRF7 activation and reduced SNARE protein expression, leading to delayed interferon responses and diminished cytokine secretion. These dual deficits may contribute to the heightened susceptibility of older individuals to severe outcomes following SARS‐CoV infection.
Yu‐Xuan Wu, Chih‐Wei Hu, Jui‐Yu Chang, Shuoh‐Wen Chen, Ting‐An Lin, Eric Chang‐Yi Lin, Min‐Hui Chen, Chuen‐Mi Yang, Hsuan‐Ying Lu, Ching‐Jung Teng, Yuan‐I Chang   +10 more
wiley   +1 more source

Role of Type I IFNs in the in Vitro Attenuation of Live, Temperature-Sensitive Vaccine Strains of Human Respiratory Syncytial Virus

, 2000
Deborah A. Loveys, Sandhya Kulkarni, Prabha L. Atreya   +2 more
openalex   +1 more source

Second‐Year Follow‐up Evaluation of Live, Attenuated Human Rotavirus Vaccine 89‐12 in Healthy Infants [PDF]

, 2002
David I. Bernstein, David A. Sack, Keith S. Reisinger, Edward Rothstein, Richard L. Ward   +4 more
openalex   +1 more source

Policy feedback and voter turnout: Evidence from the Finnish basic income experiment

American Journal of Political Science, EarlyView.
Abstract In many democracies, unemployed and low‐income citizens are less willing to vote. Can social policies weaken the link between income and turnout? We study policy feedback leveraging a unique experiment in Finland, which randomly assigned a sizable group of unemployed to receiving an unconditional basic income (BI) for 2 years (2017–19 ...
Salomo Hirvonen, Jerome Schafer, Janne Tukiainen   +2 more
wiley   +1 more source

Update on andrological effects of SARS‐CoV‐2 infection and COVID‐19: An overview review

Andrology, EarlyView.
Abstract Background Evidence indicates a wide range of andrological alterations in patients with the Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS‐CoV‐2) infection and Coronavirus Disease 2019 (COVID‐19). Aim To provide an update on the andrological effects of SARS‐CoV‐2 infection and COVID‐19.
Giuseppe Lisco, Anna De Tullio, Maima Matin, Vito Angelo Giagulli, Edoardo Guastamacchia, Giovanni De Pergola, Giuseppina Piazzolla, Vincenzo Triggiani   +7 more
wiley   +1 more source

AttenuatedYersiniaenterocoliticaMutant Strains Exhibit Differential Virulence in Cytokine-Deficient Mice: Implications for the Development of Novel Live Carrier Vaccines [PDF]

, 2003
María Silvia Di Genaro, Marc Waidmann, Uwe Kramer, Niclas Hitziger, Erwin Bohn, Ingo B. Autenrieth   +5 more
openalex   +1 more source

The Paediatric BCG Vaccine Century: From Historical Success to Future Innovations

Acta Paediatrica, EarlyView.
ABSTRACT Aim The tuberculosis (TB) vaccine, Bacille‐Calmette‐Guérin (BCG), protects infants against severe forms of primary TB. Yet, it does not protect against pulmonary reactivation TB in adults. Methods A literature review was conducted between 1st January and 28th February 2025 using PubMed, Google Scholar and reports of the World Health ...
Stefan H. E. Kaufmann
wiley   +1 more source

A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage [PDF]

, 2017
Diamond, Michael S, et al,, Jagger, Brett W, Richner, Justin   +3 more
core   +2 more sources

Efficacy and safety of HRS‐5965 monotherapy in complement inhibitor–naïve patients with paroxysmal nocturnal haemoglobinuria

British Journal of Haematology, EarlyView.
Summary Paroxysmal nocturnal haemoglobinuria (PNH) is a rare, life‐threatening disorder characterized by complement‐mediated haemolysis, leading to anaemia and thrombosis. HRS‐5965 is a novel, oral, selective complement factor B inhibitor targeting the alternative pathway, potentially reducing both intra‐ and extravascular haemolysis.
Li Zhang, Ziwei Liu, Xin Zhao, Bin Hu, Rong Huang, Chang Shu, Fengkui Zhang, Bing Han   +7 more
wiley   +1 more source

Innovative pharmacotherapy for hepatic metabolic and chronic inflammatory diseases in China

British Journal of Pharmacology, EarlyView.
Abstract Liver disease constitutes a significant global health concern, particularly in China where it has distinctive characteristics. China grapples with a staggering 300 million cases, predominantly due to hepatitis B and metabolic non‐alcoholic fatty liver disease. Additionally, hepatocellular carcinoma has become a prevalent which is a lethal type
Feng Zhang, Jiaming Ju, Hongtao Diao, Jinglun Song, Yu bian, Baofeng Yang   +5 more
wiley   +1 more source