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Live Attenuated Oral Poliovirus Vaccine

Clinical Infectious Diseases, 1984
During 1952-1954, some of the first papers were published on the attenuation of wild poliovirus for vaccine purposes. These efforts soon came to fruition , and large-scale field trials were held in many countries under a variety of conditions. Routine use of live oral poliovirus vaccines ( OPV ) was begun in many countries during the spring of 1960 ...
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Live, Attenuated Mumps-Virus Vaccine

New England Journal of Medicine, 1968
Abstract Jeryl-Lynn strain (B level) live, attenuated mumps-virus vaccine was administered to 6283 initially susceptible children and 163 adults, including 132 males. There was no evident clinical reaction to the vaccine either in adults or in children including infants.
M R, Hilleman   +3 more
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Live Attenuated Varicella-Zoster Vaccine

Clinical Infectious Diseases, 1980
Varicella-zoster (VZ) virus causes two diseases, varicella and zoster. Because it was recognized that, after varicella, latent VZ virus persisted in the host and because varicella was thought to be a milde disease, there was little impetus in North America to develop a live VZ vaccine.
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Live Attenuated Vaccines for Pandemic Influenza

2009
In this chapter, we will review the development of and clinical experience with the currently licensed seasonal live attenuated influenza vaccines (LAIV) and preclinical studies of H5, H7, and H9 live attenuated pandemic influenza vaccine candidates. Vectored vaccine approaches will not be reviewed in this chapter.
Grace L, Chen, Kanta, Subbarao
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A live attenuated human rotavirus vaccine

Drugs of Today, 2007
Rotavirus infections are the leading cause of severe gastroenteritis in young children worldwide. This review provides a summary of the development of a live oral rotavirus vaccine, Rotarix (GlaxoSmithKline, Rixensart, Belgium) developed from a single protective G1P[8] human strain.
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Live attenuated influenza vaccine for children

Drug and Therapeutics Bulletin, 2017
For many years, the UK seasonal influenza vaccination programme has been offered to people at higher risk from the complications of influenza infection, including those aged over 65 years and anyone aged over 6 months who is in a clinical risk group.1 In 2012, the Joint Committee on Vaccination and Immunisation (JCVI) recommended extending seasonal ...
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Live attenuated vaccines for human use

Current Opinion in Biotechnology, 1992
Live attenuated vaccines have been successfully used for the prevention of a number of viral and bacterial diseases. Several vaccine strains have been utilized recently as expression vectors for cloned heterologous antigens. Through the use of recombinant DNA technology, candidate vaccine strains and vector systems have been developed and are ...
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Live attenuated vaccine for hepatitis A.

Developments in biological standardization, 1984
The successful development of hepatitis B vaccines has stimulated interest in the active immunoprophylaxis of type A hepatitis. The development of hepatitis A vaccines has been simplified by the ability to propagate HAV in tissue culture systems and the availability of animal model systems, including the chimpanzee and certain species of marmosets in ...
S M, Feinstone   +3 more
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Studies with Live Attenuated Influenza Vaccines

American Journal of Clinical Pathology, 1979
G, Florent, F, André
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