Live vaccination tactics: possible approaches for controlling visceral leishmaniasis
Frontiers in Immunology, 2014 Vaccination with durable immunity is the main goal and fundamental to control leishmaniasis. To stimulate the immune response, small numbers of parasites are necessary to be presented in the mammalian host.
Noushin eSaljoughian +2 more
doaj +1 more source
Neutropenia as an adverse event following vaccination : results from randomized clinical trials in healthy adults and systematic review [PDF]
, 2016 Background : In the context of early vaccine trials aimed at evaluating the safety profile of novel vaccines, abnormal haematological values, such as neutropenia, are often reported.
Aerssens, Annelies +10 more
core +4 more sources
Development of dengue vaccines [PDF]
, 2018 Background: Dengue virus (DENV) causes up to 390 million infections yearly, of which 96 million are clinically manifested. Approximately 500,000 people with severe dengue require hospitalization each year and there are at least 25,000 deaths among ...
Lim, Chee Siean *, Poh, Chit Laa *
core +3 more sources
Generation of DelNS1 Influenza Viruses: a Strategy for Optimizing Live Attenuated Influenza Vaccines
mBio, 2019 Nonstructural protein 1 (NS1) of influenza virus is a key virulence element with multifunctional roles in virus replication and a potent antagonist of host immune response.
Pui Wang +17 more
doaj +1 more source
Development of a novel equine influenza virus live-attenuated vaccine [PDF]
, 2018 H3N8 equine influenza virus (EIV) is an important and significant respiratory pathogen of horses. EIV is enzootic in Europe and North America, mainly due to the suboptimal efficacy of current vaccines. We describe, for the first time, the generation of a
Chambers, Thomas M. +5 more
core +1 more source
Full genome sequence-based comparative study of wild-type and vaccine strains of infectious laryngotracheitis virus from Italy [PDF]
, 2016 Infectious laryngotracheitis (ILT) is an acute and highly contagious respiratory disease of chickens caused by an alphaherpesvirus, infectious laryngotracheitis virus (ILTV).
Franchin, Elisa +8 more
core +7 more sources
Protection efficacy of Argentinian isolates of Mycobacterium avium subsp. paratuberculosis with different genotypes and virulence in a murine model [PDF]
, 2018 Paratuberculosis is a chronic disease caused by Mycobacterium avium subsp. paratuberculosis (Map). The disease causes economic losses and, therefore, it is imperative to follow proper control strategies, which should include an effective vaccine. Several
Alvarado Pinedo, María Fiorella +8 more
core +1 more source
Live-attenuated vaccination in patients with inflammatory bowel disease while continuing or after elective switch to vedolizumab [PDF]
Intestinal ResearchBackground/Aims Vedolizumab (VDZ) is a gut-selective agent with a favorable safety profile. We aimed to assess the feasibility of elective switch from other advanced therapies to VDZ and subsequent live-attenuated vaccination while continuing VDZ in ...
Hisashi Shiga +7 more
doaj +1 more source
Frontiers in Veterinary Science, 2022 Immunosuppression in poultry production is a recurrent problem worldwide, and one of the major viral immunosuppressive agents is Infectious Bursal Disease Virus (IBDV). IBDV infections are mostly controlled by using live-attenuated vaccines.
Céline Courtillon +8 more
doaj +1 more source