Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Complex coacervate tissue adhesives: effect of polycation chemistry and ionic strength on cytocompatibility. [PDF]
J Mater Sci Mater MedKwant AN +6 more
europepmc +1 more source
A new method to learn growth curves of beef cattle using a factorization approach [PDF]
, 2018 Alonso González, Jaime +3 more
core +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Association between BMI trajectories and metabolic syndrome in postmenopausal women: a cross-sectional study from NHANES 1999-2018. [PDF]
BMC Public HealthLiu Y, Liang Z, Li X, Xiong J.
europepmc +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Efficacy of a Modified-Live Virus Combination Vaccine (CDV, CAV, CPV, CPiV), Canigen<sup>TM</sup> DHPPi, in Puppies Vaccinated at Six Weeks of Age. [PDF]
VirusesLoukeri S +4 more
europepmc +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Systems approach to nitrogen modeling in the Chesapeake Bay: Advancing production chain analysis under future changes. [PDF]
J Environ QualMohammadpour P +5 more
europepmc +1 more source