Results 141 to 150 of about 222,243 (315)

Productive water uses at household level in rural Kenya: case study of the Ukambani district [PDF]

, 2006
As a result of the growing world population and enhanced by the rising of living standards, competition for water is growing and this causes increased pressure on water resources worldwide.
D'Haese, Luc, Ochieng, C, Speelman, Stijn, Vandermeulen, Valerie   +3 more
core  

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Role of non-timber forest products in sustaining forest-based livelihoods and rural households' resilience capacity in and around protected area- a Bangladesh study

, 2015
People in developing world derive a significant part of their livelihoods from various forest products, particularly non-timber forest products. This article attempts to explore the contribution of NTFPs in sustaining forest-based rural livelihood in and
Khan, N. A., Mukul, S. A., Rashid, A. Z. M. M., Uddin, M. B.   +3 more
core   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Wetland Users' Livelihood Response to Seasonal Fluctuation in Kumadugu-Yobe River Basin Wetlands

Indonesian Journal of Geography
The wetlands of kumadugu yobe river basin are the livelihood soul of the communities living around the wetlands site. The dominant pastoralist and agrarian population of the wetland site drives their livelihood directly from the wetlands.
Ahmed Abubakar Jajere, Ibrahim Ahmed Jajere, Abubakar M Said, M. I. Bammami   +3 more
doaj   +1 more source

Linking Population, Fertility and Family Planning with Adaptation to Climate Change: Views from Ethiopia [PDF]

, 2009
As global climate change unfolds, its effects are being felt disproportionately in the world's poorest countries and among the groups of people least able to cope.
Aklilu Kidanu, Karen Hardee, Kimberly Rovin   +2 more
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Investigating the Livelihoods of the Population Dependent on Natural Resources and their Concerns Regarding Climate Change

, 2012
The ACC Dar project aims to improve the effectiveness of municipal initiatives in Dar es Salaam that support the efforts of those coastal peri-urban dwellers, partially or totally dependent on natural resources, to adapt to Climate Change (CC) impacts. More specifically, the action will enhance the capacities of Dar's municipalities by increasing their
Ricci Liana, Demurtas Pietro, Macchi Silvia, Cerbara Loredana   +3 more
openaire   +3 more sources

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Agroforestry-based Livelihoods in the Face Of Cultural and Socio-economic Dynamics in Rural Gedeo, Southern Ethiopia

Journal of Rural and Community Development, 2020
This paper analyzes the vulnerability contexts of the agroforestry-based livelihoods of smallholders in rural Gedeo, Southern Ethiopia. Being extracted from a broader study that investigated the livelihood and food security situations within the ...
Fekadu Israel Alambo
doaj