Results 11 to 20 of about 338,033 (287)

M2-like macrophages exert hepatoprotection in acute-on-chronic liver failure through inhibiting necroptosis-S100A9-necroinflammation axis

open access: yesCell Death and Disease, 2021
Necroptosis has emerged as a novel and crucial player in acute and chronic liver diseases. Necroptotic cells lead to the release of DAMPs including S100A9, followed by the development of necroinflammation.
Li Bai   +5 more
doaj   +1 more source

Combined Effects of UGT1A1 and SLCO1B1 Variants on Chinese Adult Mild Unconjugated Hyperbilirubinemia

open access: yesFrontiers in Genetics, 2019
The potential for genetic variation to cause adult unconjugated hyperbilirubinemia is increasingly being recognized. However, the cumulative effects of genetic variants have not been fully illuminated.
Jie Bai   +12 more
doaj   +1 more source

Problems in Treating Experimentally Induced Acute Hepatic Failure by Hemoperfusion or Cross Circulation [PDF]

open access: yes, 1983
Acute hepatic failure was induced in rats by galactosamine injection intraperitoneally (1 gm per kg). Twenty-four hours later rats were treated by hemoperfusion (HP) over encapsulated sorbents: cellulose acetate-coated charcoal, polyelectrolyte-coated ...
Beyerbacht, Ellen C.   +3 more
core   +7 more sources

Artificial rearing influences the morphology, permeability and redox state of the gastrointestinal tract of low and normal birth weight piglets [PDF]

open access: yes, 2017
Background: In this study the physiological implications of artificial rearing were investigated. Low (LBW) and normal birth weight (NBW) piglets were compared as they might react differently to stressors caused by artificial rearing.
Casteleyn, Christophe   +9 more
core   +1 more source

Dynamic changes of phenotype and function of natural killer cells in peripheral blood before and after thermal ablation of hepatitis B associated hepatocellular carcinoma and their correlation with tumor recurrence

open access: yesBMC Cancer, 2023
Background Thermal therapy induces an immune response in patients with hepatocellular carcinoma (HCC), but the dynamic characteristics of the natural killer (NK) cell immune response post-thermal ablation remain unclear.
Hai-Yan Wang   +6 more
doaj   +1 more source

Texture features based microscopic image classification of liver cellular granuloma using artificial neural networks [PDF]

open access: yes, 2019
Automated classification of Schistosoma mansoni granulomatous microscopic images of mice liver using Artificial Intelligence (AI) technologies is a key issue for accurate diagnosis and treatment.
Chen, Gaoxiang   +6 more
core   +1 more source

The landscape of viral associations in human cancers [PDF]

open access: yes, 2020
Here, as part of the Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, for which whole-genome and—for a subset—whole-transcriptome sequencing data from 2,658 cancers across 38 tumor types was aggregated, we systematically investigated potential ...
Alawi, Malik   +14 more
core   +3 more sources

Two adolescent cases of early use of Molecular Adsorbent Recirculating System for drug-induced fulminant hepatic failure [PDF]

open access: yesPediatric Emergency Medicine Journal
Fulminant hepatic failure (FHF) is a rare but fatal disease with a 40%-80% mortality, often requiring liver transplantation, which is hard to perform in children.
Seo Yeon Kim, Beom Joon Kim
doaj   +1 more source

Drug-Induced Nephrotoxicity Assessment in 3D Cellular Models

open access: yesMicromachines, 2021
The kidneys are often involved in adverse effects and toxicity caused by exposure to foreign compounds, chemicals, and drugs. Early predictions of these influences are essential to facilitate new, safe drugs to enter the market.
Pengfei Yu   +6 more
doaj   +1 more source

Application of 3D Hepatic Plate-Like Liver Model for Statin-Induced Hepatotoxicity Evaluation

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
Background: Drug-induced liver injury is one of the main reasons of withdrawals of drugs in postmarketing stages. However, an experimental model(s) which can accurately recapitulates liver functions and reflects the level of drug hepatotoxicity is lack ...
Jiecheng Xu   +13 more
doaj   +1 more source

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