Results 21 to 30 of about 338,033 (287)
Scientific Reports, 2021 Acute-on-chronic liver failure (ACLF) is a dynamic syndrome, and sequential assessments can reflect its prognosis more accurately. Our aim was to build and validate a new scoring system to predict short-term prognosis using baseline and dynamic data in ...
Zhenjun Yu +11 more
doaj +1 more source
Usefulness of regional right ventricular and right atrial strain for prediction of early and late right ventricular failure following a left ventricular assist device implant: A machine learning approach [PDF]
, 2019 Background: Identifying candidates for left ventricular assist device surgery at risk of right ventricular failure remains difficult. The aim was to identify the most accurate predictors of right ventricular failure among clinical, biological, and ...
Agnese V. +14 more
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International Journal of Infectious Diseases, 2014 Objectives: To evaluate the progression of fibrosis and factors influencing this in interferon (IFN) treatment-naive Chinese plasma donors infected with hepatitis C virus (HCV) for approximately 20 years.
Jun-Feng Li +10 more
doaj +1 more source
Frontiers in Pharmacology, 2021 Background: Cancer is the second leading cause of death globally. However, most of the new anti-cancer agents screened by traditional drug screening methods fail in the clinic because of lack of efficacy.
Wei Liao +16 more
doaj +1 more source
Circadian and Metabolic Effects of Light: Implications in Weight Homeostasis and Health [PDF]
, 2017 Daily interactions between the hypothalamic circadian clock at the suprachiasmatic nucleus (SCN) and peripheral circadian oscillators regulate physiology and metabolism to set temporal variations in homeostatic regulation.
Diego A. Golombek +6 more
core +2 more sources
Issues of intensive care and liver transplantation tactics in fulminant liver failure
Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье, 2023 Fulminant liver failure is usually characterized as severe acute liver injury with encephalopathy and synthetic dysfunction (international normalized ratio [INR] ≥1.5) in a patient without cirrhosis or previous liver disease.
L. U. Agumava +10 more
doaj +1 more source
Journal of Immunology Research, 2014 This study aimed to investigate the role of 5-lipoxygenase (5-LO) in acute liver failure (ALF) and changes in macrophage activation by blocking it. ALF was induced in rats by administration of D-galactosamine (D-GalN)/lipopolysaccharide (LPS).
Lu Li +11 more
doaj +1 more source
Stem Cell Research & Therapy, 2020 Lineage tracing is the most widely used technique to track the migration, proliferation, and differentiation of specific cells in vivo. The currently available gene-targeting technologies have been developing for decades to study organogenesis, tissue ...
Yue Zhang +4 more
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Frontiers in Endocrinology, 2022 ObjectiveMetabolic syndrome (MetS) and non-alcoholic fatty liver disease (NAFLD) are the leading chronic diseases worldwide. There are still many controversies about the association between serum bilirubin and MetS or NAFLD.
Chen Liang +14 more
doaj +1 more source
Cross-species gene expression analysis of species specific differences in the preclinical assessment of pharmaceutical compounds [PDF]
, 2014 Animals are frequently used as model systems for determination of safety and efficacy in pharmaceutical research and development. However, significant quantitative and qualitative differences exist between humans and the animal models used in research ...
A Kuhn +36 more
core +4 more sources