Results 121 to 130 of about 1,519,715 (337)

Landscape of BRAF transcript variants in human cancer

open access: yesMolecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda   +5 more
wiley   +1 more source

The development and prospects of liver surgery

open access: yesClinical Surgical Oncology, 2023
Surgical treatment is the classic treatment modality for focal liver diseases. In 140 years, liver surgery is constantly evolving, along with advances in understanding anatomy, physiology, and emergence of technologies.
Hui-Chuan Sun   +7 more
doaj  

Liver cancer: contributory factors, diagnosis and treatment [PDF]

open access: yes, 2016
Liver cancer have high mortality secondary to hepatitis B,hepatitis C and secondary to alcohol.Hepatocellular carcinoma (HCC),most common form of liver cancer with highest rates in China and in Sub-Saharan Africa.
AM Sharifa   +6 more
core  

Painless cancer of the liver [PDF]

open access: yesTransactions of the Royal Academy of Medicine in Ireland, 1892
n ...
openaire   +3 more sources

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte   +10 more
wiley   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

Analysis of the Clinicopathological Features of Hepatocellular Carcinoma in Elderly Patients

open access: yesJournal of Nepal Medical Association, 2008
The peak age of onset of hepatocellular carcinoma (HCC) is continually increasing worlwide. This study aims to evaluate whether there exists any significant difference in the clinicopathological features between younger- and elderly-HCC.1082 Consecutive ...
Xia Jing-Lin   +7 more
doaj   +1 more source

Methionine adenosyltransferases in liver cancer. [PDF]

open access: yes, 2019
Methionine adenosyltransferases (MATs) are essential enzymes for life as they produce S-adenosylmethionine (SAMe), the biological methyl donor required for a plethora of reactions within the cell.
Barbier-Torres, Lucia   +4 more
core  

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

open access: yesMolecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy