Results 221 to 230 of about 1,519,715 (337)
The multifaceted role of microbiota in liver cancer: pathogenesis, therapy, prognosis, and immunotherapy. [PDF]
Front ImmunolFeng Y +6 more
europepmc +1 more source
Advanced Biology, EarlyView.The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li +10 more
wiley +1 more source
Patient-derived xenograft model: Applications and challenges in liver cancer. [PDF]
Chin Med J (Engl)Dou S +6 more
europepmc +1 more source
Advanced Biology, EarlyView.HMGB1 derived from the pyroptotic environment in Hirschsprung‐associated enterocolitis mediates the formation of macrophage extracellular traps through TLR4 ‐p38 MAPK/p65 NF‐kB signaling pathways. Macrophage extracellular traps induce increased ROS production and pyroptosis of colonic epithelial cells.
Rui Zhang +6 more
wiley +1 more source
The impact of diabetes and social, biologic and behavioral determinants of health on liver cancer risk. [PDF]
Front Endocrinol (Lausanne)Shouman M, Jaffa AA, Jaffa MA.
europepmc +1 more source
The Regulation of Trace Metal Elements in Cancer Ferroptosis
Advanced Biology, EarlyView.The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang +5 more
wiley +1 more source
Advances and challenges in pathomics for liver cancer: From diagnosis to prognostic stratification. [PDF]
World J Clin OncolPeng MH +4 more
europepmc +1 more source