Results 61 to 70 of about 300,444 (267)
Circulating miRNAs in nontumoral liver diseases
Pharmacological Research, 2018 In recent years, there has been increasing interest in finding new biomarkers for diagnosis and prognostication of liver diseases. MicroRNAs (miRNAs) are small noncoding RNA molecules involved in the regulation of gene expression and have been studied in relation to several conditions, including liver disease. Mature miRNAs can reach the bloodstream by
Alex Evangelista, do Amaral +3 more
openaire +2 more sources
Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
FEBS Open Bio, EarlyView.This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source
Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection
FEBS Open Bio, EarlyView.Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow +12 more
wiley +1 more source
Canadian Journal of Gastroenterology, 1987 The reticuloendothelial system of patients with ulcerative colitis and associated liver disease is impaired in its ability to clear immune complex-like material from the systemic circulation.
G.Y. Minuk +7 more
doaj +1 more source
Role of circulating microRNAs in liver diseases
World Journal of Hepatology, 2017 MicroRNAs (miRNAs) are small RNAs regulate gene expression by inhibiting the turnover of their target mRNAs. In the last years, it became apparent that miRNAs are released into the circulation and circulating miRNAs emerged as a new class of biomarkers for various diseases. In this review we summarize available data on the role of circulating miRNAs in
Loosen, Sven H +4 more
openaire +2 more sources
FEBS Open Bio, EarlyView.The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti +5 more
wiley +1 more source
PHYSIOLOGY OF CHOLESTEROL METABOLISM (THE REVIEW)
Acta Biomedica Scientifica, 2012 There are two sources of cholesterol: endogenous (biliary) and exogenous (dietary) in human organism. Biliary cholesterol arrives with cyctic and. hepatic bile in small intestine and. is mixed, with dietary cholesterol.
YA. L. Tyuryumin +2 more
doaj
Medication Rule of Traditional Chinese Medicine on Primary Hepatocellular Carcinoma with Ascites
Zhongliu Fangzhi Yanjiu, 2019 Object To explore the clinical medication rule and feature of TCM on hepatocellular carcinoma with ascites. Methods We collected the clinical data of 186 hepatocellular carcinoma patients with ascites, established the clinical drugs database, and used ...
ZHANG Fan +5 more
doaj +1 more source
Metformin exposure, maternal PCOS status and fetal venous liver circulation: A randomized, placebo-controlled study. [PDF]
PLoS One, 2022 Grindheim S +8 more
europepmc +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source