Results 71 to 80 of about 300,444 (267)

Effects of curcumin on the signal transducer and activator of transcription 3 signaling pathway and bile acid enterohepatic circulation in liver cancer mice model

Pakistan Journal of Pharmaceutical Sciences
Background: Liver cancer has a high incidence and poor prognosis. Curcumin is a natural compound with anti-tumor activity, but its effects on the STAT3 signaling pathway and the bile acid enterohepatic circulation in liver cancer models remain unclear ...
Na Hu, Niu Yan, Tingting Zhao, Langui Hu
doaj   +1 more source

Maintenance of Minute Circulation Volume during Orthotopic Liver Transplantation

Общая реаниматология, 2011
Objective: to optimize procedures to maintain minute circulation volume at different stages of orthotopic liver transplantation. Subjects and methods.
D. A. Levit, E. A. Chvanov, Yu. I. Petrishchev, A. L. Levit   +3 more
doaj   +1 more source

Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants

Annals of Clinical and Translational Neurology, EarlyView.
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold, Krzysztof W. Selmaj, Regina Berkovich, Jeffrey A. Cohen, Giancarlo Comi, Eva K. Havrdová, James K. Sheffield, Hetal Desai, Chun‐Yen Cheng, Jon V. Riolo, Andrew Thorpe, Erik DeBoer, Bruce A. C. Cree   +12 more
wiley   +1 more source

The unusual location of primary hydatid cyst: A case series study

Open Medicine
Cystic echinococcosis mainly affects the liver and lungs, in which the larvae from the microvascular wall in the liver pass to the lungs and then to the blood circulation and settle in any tissue or organ.
Qaradaghy Seerwan Hama Shareef, Ismael Diyaree Nihad, Ameen Shorsh Hama Hussein, Mahmood Kawa Abdula, Aghaways Ismael Hama Amin, Shakor Fadhluddin Nasruddin, Abdullah Zana Othman, Ibrahim Kawa M., Omer Mohammed Amin Ali, Mohammed Sangar Abdullah, Mohammed Aram Ahmed, Rasheed Safeen Hama   +11 more
doaj   +1 more source

Liver Circulation and Common Duct Obstruction

Experimental Biology and Medicine, 1954
Summary1. Excision of the hepatic artery combined with obstruction of the common bile duct has a high mortality. Administration of antibiotics was not able to prevent anaerobic growth and liver necrosis in some of these dogs. 2. If the above 2 procedures are performed in 2 stages, mortality is somewhat lower if excision of the hepatic artery is done ...
N C, JEFFERSON, H L, POPPER, H, NECHELES
openaire   +2 more sources

Added Prognostic Value of EEG Reactivity in Comatose Patients Following Cardiac Arrest

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the added prognostic value of EEG reactivity for favorable outcome compared with background analysis during and after targeted temperature management (TTM). Methods Prospective observational cohort study of comatose post–cardiac arrest patients admitted to a single academic center between 2017 and 2022, all undergoing ...
Sarah Caroyer, Marie Obrecht, Charlotte de Maeseneire, Charlotte Damien, Chantal Depondt, Lorenzo Ferlini, Estelle Rikir, Filippo Annoni, Fabio Silvio Taccone, Nicolas Mavroudakis, Benjamin Legros, Nicolas Gaspard   +11 more
wiley   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily   +5 more
wiley   +1 more source

Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong, Sebastian Díaz‐Pérez, Kevin Navin Sheth, Jang‐Ho Cha, C. J. Malanga, Patricia G. M. Wagner, Nicole Pezous, Aurelie Hanin, Kyle B. Walsh, H. E. Hinson, Lauren Hachmann Sansing   +10 more
wiley   +1 more source

Circulating microRNAs as a Fingerprint for Liver Cirrhosis

PLoS ONE, 2013
Sensitive and specific detection of liver cirrhosis is an urgent need for optimal individualized management of disease activity. Substantial studies have identified circulation miRNAs as biomarkers for diverse diseases including chronic liver diseases.
Yan-Jie Chen, Ji-Min Zhu, Hao Wu, Jia Fan, Jian Zhou, Jie Hu, Qian Yu, Tao-Tao Liu, Lei Yang, Chun-Lei Wu, Xiao-Ling Guo, Xiao-Wu Huang, Xi-Zhong Shen   +12 more
openaire   +4 more sources