Results 81 to 90 of about 59,179 (315)

Predictors of liver failure in primary biliary cirrhosis

Upsala Journal of Medical Sciences, 2014
The disease progression of patients with primary biliary cirrhosis (PBC) varies significantly, and the prognostic markers that identify those patients who will develop liver failure have been scarcely studied from a Chinese cohort. Aims. We aimed to determine the predictive factors of liver failure in patients with PBC.Patients who were first diagnosed
Zhao, Pan, Liu, Wei-wei, Li, Jin-feng, Wang, Chun-ya, Wang, Hao, Xu, Jun, Wang, Rui-fang, Yang, Hao-zhen, Jin, Cheng, Wei, Zhen-man   +9 more
openaire   +2 more sources

Hypothalamic Control of Liver Health and Disease: From Circuits to Pathophysiology and Therapies

Advanced Science, EarlyView.
This review delineates the hypothalamic circuits that control liver homeostasis via autonomic and neuroendocrine pathways. Dysregulation of this hypothalamus–liver axis drives disease progression across a spectrum including steatotic liver disease, liver inflammation and injury, fibrosis, cirrhosis, and hepatocellular carcinoma.
Qin Tang, Jiahui Li, Haiying Song, Ailin Zhang, Haifeng Zeng, Yining Xu, Li Mo, Jinhan He   +7 more
wiley   +1 more source

Obstructive Biliary Cirrhosis in a Cat Due to Platynosomum Fastosum Infection

Revista Científica, 2009
Biliary cirrhosis is rare in domestic animals and has scarcely been reported in cats. Most cases of biliary cirrhosis in cats are related to parasitic infections by Amphimerus pseudofelineus, Metorchis complexus, and Opistorchis pseudofelineus. A case of
Jorge A. Soto, Amri Villalobos, Cruz M. Arraga de Alvarado, Angel R. Chirinos   +3 more
doaj  

Ahcy Acts as an Effector of Hnf4a‐Driven Super‐Enhancer Activation to Alleviate MASLD During Intermittent Fasting

Advanced Science, EarlyView.
Our study identifies an Hnf4a‐driven super‐enhancer of hepatic Ahcy that mediates the protective effects of intermittent fasting against MASLD. Disruption of the Ahcy super‐enhancer reduces Ahcy expression and exacerbates lipid accumulation. This pathway prevents aberrant promoter hypermethylation by maintaining the SAM/SAH balance, as exemplified by ...
Huafeng Chen, Shilin Zhang, Xiaojie Deng, Wenqiang Xie, Fen Xu, Jie Shen, Hua Liang   +6 more
wiley   +1 more source

Imaging of Hepatocellular Carcinoma by Computed Tomography and Magnetic Resonance Imaging: State of the Art [PDF]

, 2009
Hepatocellular carcinoma (HCC) is a very frequent tumor worldwide. Its incidence is linked to the distribution of liver cirrhosis and viral hepatitis, which are the main risk factors for the development of HCC.
Reiser, Maximilian F., Herrmann, Karin A., Zech, Christoph J.   +2 more
core   +1 more source

Primary biliary cirrhosis presenting with ascites and a hepatic hydrothorax: a case report

Journal of Medical Case Reports, 2009
Introduction We report an unusual presentation of primary biliary cirrhosis. Case presentation We present the case of a 66-year-old white British woman who presented to the Accident and Emergency department with ascites and unilateral pleural effusion ...
Wojcikiewicz Thomas George, Gupta Sachin
doaj   +1 more source

Recent Advances in Functional Liver Volumetry: Emphasis on 99mTc‐GSA SPECT/CT Fusion Imaging

Annals of Gastroenterological Surgery, EarlyView.
Functional liver volumetry enables more accurate assessment of the future liver remnant by integrating anatomical and functional information, improving risk stratification before major hepatectomy. Among available techniques, 99mTc‐GSA SPECT/CT fusion imaging enables precise regional functional assessment and more reliable prediction of post ...
Toru Beppu, Toshiro Masuda, Yasunori Nagayama, Hidetoshi Nitta, Hiromitsu Hayashi   +4 more
wiley   +1 more source

Recombinant Human Thrombopoietin Reduces the Need for Platelet Transfusion in Patients With Chronic Liver Disease and Thrombocytopenia

American Journal of Hematology, EarlyView.
ABSTRACT Chronic liver disease (CLD)‐related thrombocytopenia can limit the feasibility of invasive procedures. Recombinant human thrombopoietin (rhTPO) has demonstrated a favorable safety profile without hepatotoxicity. We evaluated the efficacy and safety of rhTPO in patients with CLD‐related thrombocytopenia who were undergoing elective invasive ...
Yifan Han, Ning Lin, Jinghang Xu, Sikui Wang, Jinglan Jin, Jia Shang, Yongning Xin, Youwen Tan, Dazhi Zhang, Jinlin Hou, Ping An, Wen Xie, Yujuan Guan, Qingfang Xiong, Hong Wu, Huiguo Ding, Yu Chen, Rongkuan Li, Zhili Wen, Mingqin Lu, Jinhui Yang, Zhongyin Zhou, Yongjian Zhou, Zujiang Yu, Kecan Lin, Wei Wang, Yan Huang, Yuemin Nan, Xinhua Luo, Rongshu Shi, Yi Kang, Tao Han, Shiyan Chen, Kai Wang, Yunfeng Shan, Jiaping Li, Pingguo Liu, Zheng Lu, Jun Chen, Zhen Liu, Liaoyun Zhang, Li Yang, Jifang Sheng, Zhan Zeng, Yanyan Yu, Xiaoyuan Xu   +45 more
wiley   +1 more source

Cystic fibrosis related chronic liver disease: a study of its influence upon prognosis and possible mechanisms for this; with specific reference to pulmonary and systemic haemodynamics [PDF]

, 1995
MDTo assess the influence of chronic liver disease on survival a time dependent multivariate Cox regression analysis was It performed. The results confirmed that patients with evidence of chronic liver disease have a worse prognosis.
Williams, Simon Graham John
core  

Simvastatin Attenuates Liver Injury in Rodents with Biliary Cirrhosis Submitted to Hemorrhage/Resuscitation. [PDF]

, 2017
Liver function deterioration is a major cause of death in variceal bleeding. The effects of bleeding on intrahepatic microvascular dysfunction, which contributes to liver injury in cirrhosis, are largely unknown.
Lozano, Juan Jose, Pasarin, Marcos, Bosch, Jaime, Abraldes, Juan G, García-Pagán, Juan Carlos, García-Calderó, Héctor, Gracia-Sancho, Jordi, Meireles, Cintia Zimmermann   +7 more
core   +1 more source