Results 181 to 190 of about 73,718 (217)

Serum HMGB1 and Alcohol-Related Liver Disease. [PDF]

J Clin Med
Popiolek I, Hydzik P, Ciszowski K, Balicka-Slusarczyk B, Gomolka E, Szkolnicka B, Skladany L, Arab JP, Grgurevic I, Kukla M.   +9 more
europepmc   +1 more source

Physiologically based pharmacokinetic modeling and simulation of topiramate in populations with renal and hepatic impairment and considerations for drug–drug interactions

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 510-522, March 2025.
Abstract Topiramate (TPM) is a broad‐spectrum antiepileptic drug (AED) commonly prescribed for approved and off‐label uses. Routine monitoring is suggested for clinical usage of TPM in special population due to its broad side effect profile. Therefore, it is crucial to further explore its pharmacokinetic characteristics.
Shuqing Chen, Chaozhuang Shen, Yuchen Tian, Yuhe Peng, Jing Hu, Haitang Xie, Ping Yin   +6 more
wiley   +1 more source

Zinc supplementation in liver cirrhosis: meta-analysis of its effect on biochemical and clinical outcomes. [PDF]

BMC Nutr
Gong Y, Yang Z, Sun G, Xue X, Zhang X.
europepmc   +1 more source

Disease Progression Mathematical Modeling With a Case Study on Hepatitis B Virus Infection

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 420-434, March 2025.
ABSTRACT Chronic Hepatitis B presents a significant health and socioeconomic burden. The risk of hepatocellular carcinoma remains elevated although treatments are available. Achieving an optimal treatment regimen necessitates a deep comprehension of the dynamic relationship between the virus and its host across disease states.
Clémence Boivin‐Champeaux, Nieves Velez de Mendizabal, Aksana Jones, Scott Balsitis, Stephan Schmidt, Justin S. Feigelman, Francine Johansson Azeredo   +6 more
wiley   +1 more source

THE IL-6/IL-10 INFLAMMATORY AXIS AND PROGNOSIS OF CIRRHOSIS-ASSOCIATED HEPATOCELLULAR CARCINOMA: A NARRATIVE REVIEW. [PDF]

Arq Gastroenterol
Rezende RB.
europepmc   +1 more source

Hormone Replacement Therapy for Menopausal Symptoms and the Risk of Cardiometabolic Disease: Current Evidence and Future Directions

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Background The transition through menopause is accompanied by a series of adverse metabolic changes which are associated with an increased risk of cardiometabolic disease, a major cause of mortality in women after midlife. Whilst the indication for menopausal hormone replacement therapy (HRT) is the control of menopausal symptoms ...
Jiawen Dong, Sarah Hillman, Sharon Dixon, Anupa Shah, Radha Venkatakrishnan, Jeremy W. Tomlinson   +5 more
wiley   +1 more source

Microbiome and metabolite signatures for cirrhosis to HCC risk stratification: progress, controversies, and gaps. [PDF]

Front Cell Infect Microbiol
Duan Y, Yang M, Li M, Sun Y, Liu S.
europepmc   +1 more source

Development and internal validation of the SCAN score: a pragmatic bedside tool for early prediction of spontaneous bacterial peritonitis in patients with cirrhosis and ascites. [PDF]

Clin Exp Hepatol
Özden Y, Sağlam O.
europepmc   +1 more source

The Efficacy of Gut Microbiome-Modulating Therapies on Liver Cirrhosis: A Systematic Review and Network Meta-Analysis. [PDF]

Clin Transl Gastroenterol
Wang Y, OuYang J, Zhang H, Shen Y, Guo Z, Lv W.   +5 more
europepmc   +1 more source

Association of Transforming Growth Factor-β1 and α-Smooth Muscle Actin in Experimental Selective Obstructive Cholestasis. [PDF]

In Vivo
Ailioaie RC, Ciuce C, Fagarasan V, Ionescu C, Scurtu RR.   +4 more
europepmc   +1 more source