Informatics in Medicine Unlocked, 2021 Despite the fact that liver biopsy is considered to be the gold standard for detecting diffuse liver diseases, it is an invasive method with numerous side effects.
Pezhman Pasyar +6 more
doaj +1 more source
Interleukin-22 predicts severity and death in advanced liver cirrhosis: a prospective cohort study [PDF]
, 2012 Background: Interleukin-22 (IL-22), recently identified as a crucial parameter of pathology in experimental liver damage, may determine survival in clinical end-stage liver disease.
Bachmann, Malte +11 more
core +1 more source
Skeletal muscle myopenia in mice model of bile duct ligation and carbon tetrachloride-induced liver cirrhosis [PDF]
, 2017 Skeletal muscle myopathy is universal in cirrhotic patients, however, little is known about the main mechanisms involved. The study aims to investigate skeletal muscle morphological, histological, and functional modifications in experimental models of ...
Ascenzi, Francesca +11 more
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EXPERIMENTAL CIRRHOSIS: LIVER MORPHOLOGY AND FUNCTION
Wiadomości Lekarskie, 2020 The aim was to establish the morphofunctional changes of liver in the experimental cirrhosis. Materials and methods: The research was conducted on 24 white male Wistar rats. Experimental cirrhosis of the liver was simulated by oral administration of CCl4 2 g/kg 2 times weekly for three months.
Vitalij А, Datsko +6 more
openaire +2 more sources
Repopulating Kupffer cells originate directly from hematopoietic stem cells
Stem Cell Research & Therapy, 2023 Background Kupffer cells (KCs) originate from yolk-sac progenitors before birth. Throughout adulthood, they self-maintain independently from the input of circulating monocytes (MOs) at a steady state and are replenished within 2 weeks after having been ...
Xu Fan +13 more
doaj +1 more source
The bile duct ligated rat : a relevant model to study muscle mass loss in cirrhosis [PDF]
, 2016 Muscle mass loss and hepatic encephalopathy (complex neuropsychiatric disorder) are serious complications of chronic liver disease (cirrhosis) which impact negatively on clinical outcome and quality of life and increase mortality.
Bosoi, Cristina R. +7 more
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Primary Alcohol-Activated Human and Mouse Hepatic Stellate Cells Share Similarities in Gene-Expression Profiles. [PDF]
, 2020 Alcoholic liver disease (ALD) is a leading cause of cirrhosis in the United States, which is characterized by extensive deposition of extracellular matrix proteins and formation of a fibrous scar.
Baglieri, Jacopo +16 more
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Image Correction Methods for Regions of Interest in Liver Cirrhosis Classification on CNNs
Sensors, 2022 The average error rate in liver cirrhosis classification on B-mode ultrasound images using the traditional pattern recognition approach is still too high.
Yoshihiro Mitani +4 more
doaj +1 more source
Ammonia toxicity: from head to toe? [PDF]
, 2016 Ammonia is diffused and transported across all plasma membranes. This entails that hyperammonemia leads to an increase in ammonia in all organs and tissues.
Dasarathy, Srinivasan +6 more
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Experimental Liver Cirrhosis Inhibits Restenosis after Balloon Angioplasty
International Journal of Molecular Sciences, 2023 The effect of liver cirrhosis on vascular remodeling in vivo remains unknown. Therefore, this study investigates the influence of cholestatic liver cirrhosis on carotid arterial remodeling. A total of 79 male Sprague Dawley rats underwent bile duct ligation (cirrhotic group) or sham surgery (control group) and 28 days later left carotid artery balloon ...
Mare Mechelinck +9 more
openaire +3 more sources