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Despite the fact that liver biopsy is considered to be the gold standard for detecting diffuse liver diseases, it is an invasive method with numerous side effects.
Pezhman Pasyar +6 more
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EXPERIMENTAL ALCOHOLIC CIRRHOSIS OF THE LIVER [PDF]
Ever since the experimental method has been used in pathology numerous attempts have been made to show the connection between cirrhosis of the liver as often seen in "steady drinkers" and alcohol as the causative factor. In this experimental work alcohol has been used subcutaneously, intravenously, by inhalation, and fed by mouth.
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TGF-β1 Induces the Dual Regulation of Hepatic Progenitor Cells with Both Anti- and Proliver Fibrosis
Transforming growth factor-beta 1 (TGF-β1) plays a central role in hepatic progenitor cells- (HPCs-) mediated liver repair and fibrosis. However, different effects of TGF-β1 on progenitor cells have not been described.
Ai-Ting Yang +9 more
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Repopulating Kupffer cells originate directly from hematopoietic stem cells
Background Kupffer cells (KCs) originate from yolk-sac progenitors before birth. Throughout adulthood, they self-maintain independently from the input of circulating monocytes (MOs) at a steady state and are replenished within 2 weeks after having been ...
Xu Fan +13 more
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Image Correction Methods for Regions of Interest in Liver Cirrhosis Classification on CNNs
The average error rate in liver cirrhosis classification on B-mode ultrasound images using the traditional pattern recognition approach is still too high.
Yoshihiro Mitani +4 more
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Experimental Cirrhosis of the Liver [PDF]
The reparative process which follows the wide spread necrosis of the dog's liver caused by the injection of hæmagglutinative serum constitutes a chronic interstitial hepatitis of definite and constant character. This is not only a new type of experimental hepatic lesion, but is more definitely a cirrhosis than is any other experimental lesion hitherto ...
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IntroductionCirrhosis is one of the most important risk factors for development of hepatocellular carcinoma (HCC). Recent studies have shown that removal or well control of the underlying cause could reduce but not eliminate the risk of HCC.
Shan Shan +7 more
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EXPERIMENTAL CIRRHOSIS: LIVER MORPHOLOGY AND FUNCTION
The aim was to establish the morphofunctional changes of liver in the experimental cirrhosis. Materials and methods: The research was conducted on 24 white male Wistar rats. Experimental cirrhosis of the liver was simulated by oral administration of CCl4 2 g/kg 2 times weekly for three months.
Vitalij А, Datsko +6 more
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Advances on TGF-β/Smad signal pathway in hepatic fibrosis
The transforming growth factor-β (TGF-β) signaling pathway plays a vital role in regulating cell processes. As far as the liver is concerned, the TGF-β signaling pathway runs through liver diseases, from theinitial liver cell injury to inflammation ...
Han Daoning, Su Xiulan
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Fatty-acid-binding proteins (FABPs) are small intracellular proteins that coordinate lipid-mediated processes by targeting metabolic and immune response pathways.
Isabel Graupera +16 more
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