Serum microRNA-122 predicts survival in patients with liver cirrhosis [PDF]
Background: Liver cirrhosis is associated with high morbidity and mortality. MicroRNAs (miRs) circulating in the blood are an emerging new class of biomarkers.
Stefan Zeuzem +17 more
core +2 more sources
Aflatoxin exposure and viral hepatitis in the etiology of liver cirrhosis in the Gambia, West Africa. [PDF]
BACKGROUND: Cirrhosis of the liver is thought to be a major cause of morbidity and mortality in sub-Saharan Africa, but few controlled studies on the etiology of cirrhosis have been conducted in this region.
James J. Goedert +21 more
core +1 more source
EXPERIMENTAL ALCOHOLIC CIRRHOSIS OF THE LIVER [PDF]
Ever since the experimental method has been used in pathology numerous attempts have been made to show the connection between cirrhosis of the liver as often seen in "steady drinkers" and alcohol as the causative factor. In this experimental work alcohol has been used subcutaneously, intravenously, by inhalation, and fed by mouth.
openaire +1 more source
Drug-related problems and dosage adjustment in patients with liver disease [PDF]
The liver is essential for the metabolism of medicinal substances. Liver disease, especially liver cirrhosis, may lead to various pharmacokinetic and pharmacodynamic changes, predisposing patients with liver cirrhosis to adverse drug events (ADEs).
Franz, Carmen Carina
core +1 more source
Ornipressin in the treatment of functional renal failure in decompensated liver cirrhosis [PDF]
In 11 patients with decompensated cirrhosis and deteriorating renal function, the effect of the vasoconstrictor substance 8-ornithin vasopressin (ornipressin; POR 8; Sandoz, Basel, Switzerland) on renal function, hemodynamic parameters, and humoral ...
Reither, H. +8 more
core +1 more source
TGF-β1 Induces the Dual Regulation of Hepatic Progenitor Cells with Both Anti- and Proliver Fibrosis
Transforming growth factor-beta 1 (TGF-β1) plays a central role in hepatic progenitor cells- (HPCs-) mediated liver repair and fibrosis. However, different effects of TGF-β1 on progenitor cells have not been described.
Ai-Ting Yang +9 more
doaj +1 more source
Repopulating Kupffer cells originate directly from hematopoietic stem cells
Background Kupffer cells (KCs) originate from yolk-sac progenitors before birth. Throughout adulthood, they self-maintain independently from the input of circulating monocytes (MOs) at a steady state and are replenished within 2 weeks after having been ...
Xu Fan +13 more
doaj +1 more source
Experimental Cirrhosis of the Liver [PDF]
The reparative process which follows the wide spread necrosis of the dog's liver caused by the injection of hæmagglutinative serum constitutes a chronic interstitial hepatitis of definite and constant character. This is not only a new type of experimental hepatic lesion, but is more definitely a cirrhosis than is any other experimental lesion hitherto ...
openaire +2 more sources
Intrarenal Resistance Index as a Prognostic Parameter in Patients with Liver Cirrhosis Compared with Other Hepatic Scoring Systems [PDF]
Background and Aims: Patients with advanced liver cirrhosis who develop renal dysfunction have a poor prognosis. Elevated intrarenal resistance indices (RIs) due to renal vascular constriction have been described before in cirrhotic patients.
Kaiser, C. +7 more
core +1 more source
IntroductionCirrhosis is one of the most important risk factors for development of hepatocellular carcinoma (HCC). Recent studies have shown that removal or well control of the underlying cause could reduce but not eliminate the risk of HCC.
Shan Shan +7 more
doaj +1 more source

