Results 21 to 30 of about 120,185 (315)
TGF-β1 Induces the Dual Regulation of Hepatic Progenitor Cells with Both Anti- and Proliver Fibrosis
Stem Cells International, 2016 Transforming growth factor-beta 1 (TGF-β1) plays a central role in hepatic progenitor cells- (HPCs-) mediated liver repair and fibrosis. However, different effects of TGF-β1 on progenitor cells have not been described.
Ai-Ting Yang +9 more
doaj +1 more source
Experimental Cirrhosis of the Liver [PDF]
The American Journal of the Medical Sciences, 1904 The reparative process which follows the wide spread necrosis of the dog's liver caused by the injection of hæmagglutinative serum constitutes a chronic interstitial hepatitis of definite and constant character. This is not only a new type of experimental hepatic lesion, but is more definitely a cirrhosis than is any other experimental lesion hitherto ...
openaire +2 more sources
Frontiers in Genetics, 2019 IntroductionCirrhosis is one of the most important risk factors for development of hepatocellular carcinoma (HCC). Recent studies have shown that removal or well control of the underlying cause could reduce but not eliminate the risk of HCC.
Shan Shan +7 more
doaj +1 more source
Toll-like receptor-mediated signaling cascade as a regulator of the inflammation network during alcoholic liver disease [PDF]
, 2014 Chronic abuse of alcohol leads to various histological abnormalities in the liver. These are conditions collectively known as alcoholic liver disease (ALD). Currently, ALD is considered to be one of the major causes of death worldwide.
Alisi, A., Ceccarelli, S, Nobili, V
core +1 more source
Studies of liver phosphorylase in hepatic injuries. I. Alteration in enzyme activity [PDF]
, 1978 Phosphorylase activities (total and a form) were determined in the livers of experimental hepatic injuries with carbon tetrachloride or galactosamine and the livers of patients with liver diseases.
Kobayashi, Michio
core +1 more source
Advances on TGF-β/Smad signal pathway in hepatic fibrosis
生物医学转化, 2021 The transforming growth factor-β (TGF-β) signaling pathway plays a vital role in regulating cell processes. As far as the liver is concerned, the TGF-β signaling pathway runs through liver diseases, from theinitial liver cell injury to inflammation ...
Han Daoning, Su Xiulan
doaj +1 more source
IL28B is associated with outcomes of chronic HBV infection [PDF]
, 2015 Purpose The role of IL28B gene variants and expression in hepatitis B virus (HBV) infections are not well understood. Here, we evaluated whether IL28B gene expression and rs12979860 variations are associated with HBV outcomes.
Chi, Xiumei +11 more
core +1 more source
Scientific Reports, 2017 Fatty-acid-binding proteins (FABPs) are small intracellular proteins that coordinate lipid-mediated processes by targeting metabolic and immune response pathways.
Isabel Graupera +16 more
doaj +1 more source
Prospects of Antiangiogenic Therapy for Portal Hypertension in Liver Cirrhosis
Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2018 Aim. This paper is aimed at reviewing existing literature that investigates the role of angiogenesis in portal hypertension pathogenesis in liver cirrhosis and the possibilities of its antiangiogenic therapy, along with the description of angiogenesis ...
D. V. Garbuzenko
doaj +1 more source
Egyptian Liver Journal, 2021 Background HCV is a major risk factor for HCC; however, the exact mechanism of hepatocarcinogenesis is still not fully understood. Host genetic factors have been reported to play a significant role.
Ghada M. Galal +7 more
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