Results 21 to 30 of about 73,718 (217)

Prospects of Antiangiogenic Therapy for Portal Hypertension in Liver Cirrhosis

Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2018
Aim. This paper is aimed at reviewing existing literature that investigates the role of angiogenesis in portal hypertension pathogenesis in liver cirrhosis and the possibilities of its antiangiogenic therapy, along with the description of angiogenesis ...
D. V. Garbuzenko
doaj   +1 more source

Vitamin D receptor gene polymorphisms and risk of hepatocellular carcinoma in hepatitis C-related liver cirrhosis

Egyptian Liver Journal, 2021
Background HCV is a major risk factor for HCC; however, the exact mechanism of hepatocarcinogenesis is still not fully understood. Host genetic factors have been reported to play a significant role.
Ghada M. Galal, Ahmad Abudeif, Nagwa Sayed Ahmed, Nahed Fathallah Fahmy, Abeer Sheneef, Elsayed Mostafa Ali, Usama M. Abdelaal, Asmaa Naser Mohammad   +7 more
doaj   +1 more source

Lipocalin‐2 activates hepatic stellate cells and promotes nonalcoholic steatohepatitis in high‐fat diet–fed Ob/Ob mice

Hepatology, EarlyView., 2022
Graphical summary of obesity‐induced NASH progression by LCN2 targeted to HSC activation. Abstract Background and Aims In obesity and type 2 diabetes mellitus, leptin promotes insulin resistance and contributes to the progression of NASH via activation of hepatic stellate cells (HSCs).
Kyung Eun Kim, Jaewoong Lee, Hyun Joo Shin, Eun Ae Jeong, Hye Min Jang, Yu Jeong Ahn, Hyeong Seok An, Jong Youl Lee, Meong Cheol Shin, Soo Kyoung Kim, Won Gi Yoo, Won Ho Kim, Gu Seob Roh   +12 more
wiley   +1 more source

Ketorolac pharmacokinetics in experimental cirrhosis by bile duct ligation in the rat

Annals of Hepatology, 2003
The purpose of the present work was to study the pharmacokinetics of ketorolac, a poorly metabolized drug, in experimental cirrhosis. Cirrhosis was induced by bile duct ligation (BDL) for four weeks in male Wistar rats. Ketorolac was given intravenously (
Liliana Rivera-Espinosa, PhD, Pablo Muriel, PhD, Mónica Ordaz Gallo, PhD, José Pérez-Urizar, PhD, Antonio Palma-Aguirre, PhD, Gilberto Castañeda-Hernández, PhD   +5 more
doaj   +1 more source

Contemporary management of pain in cirrhosis: Toward precision therapy for pain

Hepatology, EarlyView., 2022
Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman, Neehar Parikh, Dan J. Clauw, David A. Williams, Elliot B. Tapper   +4 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

IL‐31 levels correlate with pruritus in patients with cholestatic and metabolic liver diseases and is farnesoid X receptor responsive in NASH

Hepatology, EarlyView., 2022
IL‐31 levels correlate with pruritus in patients with cholestatic and metabolic liver diseases Abstract Background and Aims Pruritus is associated with multiple liver diseases, particularly those with cholestasis, but the mechanism remains incompletely understood.
Jun Xu, Ya Wang, Mina Khoshdeli, Matt Peach, Jen‐Chieh Chuang, Julie Lin, Wen‐Wei Tsai, Sangeetha Mahadevan, Wesley Minto, Lauri Diehl, Ruchi Gupta, Michael Trauner, Keyur Patel, Mazen Noureddin, Kris V. Kowdley, Aliya Gulamhusein, Christopher L. Bowlus, Ryan S. Huss, Robert P. Myers, Chuhan Chung, Andrew N. Billin   +20 more
wiley   +1 more source

Experimental models for induction of liver cirrhosis in animals: a review [PDF]

Biotemas, 2010
The liver plays a key role in the homeostatic balance of many biological processes. Cirrhosis is a syndrome in which chronic liver diseases converge, leading to hepatocellular injury, the exacerbated deposition of fibrous tissue, and eventually the ...
Cristiane Carlin Passos, Amanda Olivotti Ferreira, Francisco Javier Hernandez Blazquez, Ricardo Romão Guerra   +3 more
doaj  

Stimulation of Liver Regeneration Using a Titanium Nickelide Implant (Experimental Study)

Acta Biomedica Scientifica, 2020
Currently, morbidity and mortality from chronic diffuse diseases of the liver and cirrhosis continue to increase worldwide. The difficulty of stabilizing the process with pharmacological agents, lots of restrictions for liver transplantation, the ...
I. R. Vesir, G. Ts. Dambaev, V. E. Gunter, E. A. Gereng, A. N. Vusik, N. E. Kurtseitov, M. M. Solovev, O. A. Fatushina, E. A. Avdoshina, I. M. Mominov   +9 more
doaj   +1 more source

Deep Learning Based Hybrid Classifier for Analyzing Hepatitis C in Ultrasound Images

Wasit Journal of Computer and Mathematics Science, 2022
Although liver biopsy is the gold standard for identifying diffuse liver disorders, it is an intrusive procedure with a host of negative side effects. Physician subjectivity may affect the ultrasonography diagnosis of diffuse liver disease. As a result,
hussein al-ogaili
doaj   +1 more source