GATA2 deficiency exacerbates chronic liver injury <i>via</i> disrupting hepatocyte death-regeneration balance: Clinical, histopathological, and molecular evidence. [PDF]
Chen YF +12 more
europepmc +1 more source
Abstract Objectives To investigate the prognostic significance of aspartate aminotransferase to platelet ratio index (APRI) in relation to histopathological features across the clinical course of biliary atresia (BA). Methods In this observational cohort study, we enrolled 135 BA patients with available APRI values at Kasai portoenterostomy (KPE, n ...
Nicholas Nordenheim +7 more
wiley +1 more source
Preclinical approaches to studying liver and kidney fibrosis: models and methodologies. [PDF]
Tiwari A, Singh S, Sharma RK, Kumar S.
europepmc +1 more source
Serum predictors of native liver survival post‐Kasai: Systematic review and meta‐analysis
Abstract Objectives After hepatoportoenterostomy (HPE), a minority of biliary atresia (BA) patients reach adolescence without liver transplantation. Several serum markers have been suggested to better predict post‐HPE outcomes in BA patients. We aimed to identify serum predictors of native liver survival (NLS) in post‐HPE BA patients.
Ahmad Anouti +5 more
wiley +1 more source
Gallstones and gallbladder wall thickening in patients with cirrhosis: Prevalence and clinical impact. [PDF]
Tsankof A +9 more
europepmc +1 more source
Sentinel events in pediatric hepatology: A pilot simulation curriculum
Abstract Objectives Sentinel hepatology events require robust prior experience to accurately diagnose and manage. Given the rarity of complex pediatric liver disease, gastroenterology (GI) fellows do not uniformly get exposure to these patients.
Anne Lyon +7 more
wiley +1 more source
CBP/β-Catenin Signaling in Hepatocytes Plays Pivotal Roles in MMP-7-Mediated Liver Fibrosis in a Metabolic Dysfunction-Associated Steatohepatitis Mouse Model. [PDF]
Imamura J +5 more
europepmc +1 more source
Liver stiffness in patients with Shwachman‐Diamond syndrome
Abstract Objective This case series aims to describe whether transient elastography (TE) as a marker of liver stiffness is associated with clinically important liver disease in children and young adults with Shwachman‐Diamond Syndrome (SDS). Methods All patients ≤25 years of age with genetically confirmed SDS seen in the Pediatric Gastroenterology ...
Sabina Sabharwal +5 more
wiley +1 more source
Exploring the mechanism of action of Jinqiancao granules against liver cirrhosis based on the liver-gut axis. [PDF]
Cheng FE +10 more
europepmc +1 more source
A Reproducible Ceramide Phenotype of Sepsis Across Aetiologies - A Monocenter Cohort Study. [PDF]
Pavel V +7 more
europepmc +1 more source

