Results 21 to 30 of about 119,037 (316)

Transcriptome Analysis Revealed a Highly Connected Gene Module Associated With Cirrhosis to Hepatocellular Carcinoma Development

open access: yesFrontiers in Genetics, 2019
IntroductionCirrhosis is one of the most important risk factors for development of hepatocellular carcinoma (HCC). Recent studies have shown that removal or well control of the underlying cause could reduce but not eliminate the risk of HCC.
Shan Shan   +7 more
doaj   +1 more source

Advances on TGF-β/Smad signal pathway in hepatic fibrosis

open access: yes生物医学转化, 2021
The transforming growth factor-β (TGF-β) signaling pathway plays a vital role in regulating cell processes. As far as the liver is concerned, the TGF-β signaling pathway runs through liver diseases, from theinitial liver cell injury to inflammation ...
Han Daoning, Su Xiulan
doaj   +1 more source

The relationship between gut microbiota and spontaneous bacterial peritonitis in patients with liver cirrhosis - a literature review [PDF]

open access: yes, 2019
Gut microbiota is an essential component in the pathogenesis of liver cirrhosis and its complications. There is a direct relationship between the gut and the liver called the gutliver axis through which bacteria can reach the liver through the portal ...
Fierbinteanu Braticevici, Carmen   +9 more
core   +3 more sources

Adipocyte Fatty-Acid Binding Protein is Overexpressed in Cirrhosis and Correlates with Clinical Outcomes

open access: yesScientific Reports, 2017
Fatty-acid-binding proteins (FABPs) are small intracellular proteins that coordinate lipid-mediated processes by targeting metabolic and immune response pathways.
Isabel Graupera   +16 more
doaj   +1 more source

Cancer-Associated Thrombosis in Cirrhotic Patients with Hepatocellular Carcinoma. [PDF]

open access: yes, 2018
It is common knowledge that cancer patients are more prone to develop venous thromboembolic complications (VTE). It is therefore not surprising that patients with hepatocellular carcinoma (HCC) present with a significant risk of VTE, with the portal vein
Burra, P   +5 more
core   +1 more source

Prospects of Antiangiogenic Therapy for Portal Hypertension in Liver Cirrhosis

open access: yesРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии, 2018
Aim. This paper is aimed at reviewing existing literature that investigates the role of angiogenesis in portal hypertension pathogenesis in liver cirrhosis and the possibilities of its antiangiogenic therapy, along with the description of angiogenesis ...
D. V. Garbuzenko
doaj   +1 more source

Vitamin D receptor gene polymorphisms and risk of hepatocellular carcinoma in hepatitis C-related liver cirrhosis

open access: yesEgyptian Liver Journal, 2021
Background HCV is a major risk factor for HCC; however, the exact mechanism of hepatocarcinogenesis is still not fully understood. Host genetic factors have been reported to play a significant role.
Ghada M. Galal   +7 more
doaj   +1 more source

Hepatitis C virus related cirrhosis decreased as indication to liver transplantation since the introduction of direct-acting antivirals: A single-center study [PDF]

open access: yes, 2018
AIM: To evaluate waiting list (WL) registration and liver transplantation (LT) rates in patients with hepatitis C virus (HCV)-related cirrhosis since the introduction of direct-acting antivirals (DAAs).
Angeli, Paolo   +10 more
core   +1 more source

Deep Learning Based Hybrid Classifier for Analyzing Hepatitis C in Ultrasound Images

open access: yesWasit Journal of Computer and Mathematics Science, 2022
Although liver biopsy is the gold standard for identifying diffuse liver disorders, it is an intrusive procedure with a host of negative side effects. Physician subjectivity may affect the ultrasonography diagnosis of diffuse liver disease. As a result,
hussein al-ogaili
doaj   +1 more source

Ketorolac pharmacokinetics in experimental cirrhosis by bile duct ligation in the rat

open access: yesAnnals of Hepatology, 2003
The purpose of the present work was to study the pharmacokinetics of ketorolac, a poorly metabolized drug, in experimental cirrhosis. Cirrhosis was induced by bile duct ligation (BDL) for four weeks in male Wistar rats. Ketorolac was given intravenously (
Liliana Rivera-Espinosa, PhD   +5 more
doaj   +1 more source

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