Results 161 to 170 of about 1,594,274 (317)

Nobiletin Attenuates Inflammation and Modulates Lipid Metabolism in an In Vitro Model of Intestinal Failure-Associated Liver Disease

Marta Belka, Aleksandra Gostyńska, Karina Sommerfeld-Klatta, Maciej Stawny, Violetta Krajka-Kuźniak   +4 more
openalex   +1 more source

Calcium‐sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter

FEBS Open Bio, EarlyView.
Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani, Hiroya Ueda, Ayumi Kawata, Yuki Sato, Kotomi Inomata, Hiroshi Mano, Masahiro Wada, Kenji Kobata   +7 more
wiley   +1 more source

Visual morphometry and three non-invasive markers in the evaluation of liver fibrosis in chronic liver disease [PDF]

, 2016
Swastik Agrawal, Caroline L. Hoad, Susan Francis, Indra Neil Guha, Philip Kaye, Guruprasad P. Aithal   +5 more
openalex   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Metabolic dysfunction and alcohol-associated liver disease (MetALD). [PDF]

eGastroenterology
Gao B, Arab JP, Liangpunsakul S, Ding WX, Szabo G, Mehal W, Wang H, He Y, Stärkel P, Llorente C, Schnabl B, Hwang S, Vandermerwe S, Gao Y, Zheng MH, Kim W, George J, Bataller R, Loomba R, Leggio L, Tacke F.   +20 more
europepmc   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source

NAD + in fatty liver disease: mechanistic insights and associated targets. [PDF]

Cell Biol Toxicol
Guo Y, Wang Y, Wu S, Wang Y, Liu X.
europepmc   +1 more source

The decreasing predictive power of MELD in an era of changing etiology of liver disease

, 2019
Elizabeth L. Godfrey, Tahir Malik, Jennifer C. Lai, Ayse L. Mindikoglu, Nhu Thao Nguyen Galván, Ronald T. Cotton, Christine A. O’Mahony, John A. Goss, Abbas Rana   +8 more
openalex   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

The predictive factors of hypozincemia in patients with chronic liver disease. [PDF]

J Nutr Sci
Ando S, Komori A, Yatsuhashi H, Abiru S, Yotsumoto Y.   +4 more
europepmc   +1 more source