Results 101 to 110 of about 651,421 (240)

The Upstream Pathway of mTOR-Mediated Autophagy in Liver Diseases

Cells, 2019
Autophagy, originally found in liver experiments, is a cellular process that degrades damaged organelle or protein aggregation. This process frees cells from various stress states is a cell survival mechanism under stress stimulation.
Haojie Wang, Yumei Liu, Dongmei Wang, Yaolu Xu, R. Dong, Yuxiang Yang, Q. Lv, Xiaoguang Chen, Ziqiang Zhang   +8 more
semanticscholar   +1 more source

Necroptosis in ischemia-reperfusion injury of lean and steatotic livers

Liver Research, 2019
Hepatic ischemia-reperfusion (IR) injury is a major complication during liver transplantation, liver resection, and other clinical situations. Increased hepatic IR injury in steatotic livers is a major reason for rejecting the use of steatotic livers for
Hua Sun, Tara McKeen, Hua Wang, Hong-Min Ni   +3 more
doaj  

LIFE QUALITY EVALUATION OF PATIENTS WITH NON-ALCOHOLIC FATTY LIVER DISEASE AND CONCOMITANT SUBCLINICAL HYPOTHYROIDISM

Вісник проблем біології і медицини, 2018
The article is devoted to the study of life quality as an integral indicator of health status in patients with a combination of non-alcoholic fatty liver disease (NAFLD) and subclinical hypothyroidism.
Feysa S. V., Chopei I. V., Siksai L. T., Tovt-Korshynska - M. I.   +3 more
doaj   +1 more source

Curcumin in Liver Diseases: A Systematic Review of the Cellular Mechanisms of Oxidative Stress and Clinical Perspective

Nutrients, 2018
Oxidative stress has been considered a key causing factor of liver damage induced by a variety of agents, including alcohol, drugs, viral infections, environmental pollutants and dietary components, which in turn results in progression of liver injury ...
M. Farzaei, Mahdi Zobeiri, F. Parvizi, Fardous F. El-Senduny, I. Marmouzi, E. Coy-Barrera, Rozita Naseri, S. Nabavi, R. Rahimi, M. Abdollahi   +9 more
semanticscholar   +1 more source

Alcohol Abstinence Does Not Fully Reverse Abnormalities of Mucosal-Associated Invariant T Cells in the Blood of Patients With Alcoholic Hepatitis [PDF]

, 2019
OBJECTIVES: Alcoholic hepatitis (AH) develops in approximately 30% of chronic heavy drinkers. The immune system of patients with AH is hyperactivated, yet ineffective against infectious diseases.
Bolte, Bottcher, Chan, Chayanupatkul, Chiba, Corbett, Cosgrove, Degre, Dhanda, Dusseaux, Eckle, Fergusson, Fung, Gao, Gao, Gerart, Hegde, Hengst, Jampana, Jeffery, Jiang, Kjer-Nielsen, Kurioka, Leclercq, Leeansyah, Leeansyah, Li, Liangpunsakul, Liangpunsakul, Loh, Markwick, Mutlu, Nagy, O'Shea, Pasala, Patel, Puri, Rao, Reantragoon, Riva, Saberi, Slichter, Spaan, Tang, Tilloy, Ussher, van Wilgenburg, Wong, Yong   +48 more
core   +1 more source

Depression and hepatobiliary diseases: a bidirectional Mendelian randomization study

Frontiers in Psychiatry
BackgroundMore and more evidence suggests a close association between depression and hepatobiliary diseases, but its causal relationship is not yet clear.MethodUsing genome-wide association studies (GWAS) to summarize data, independent genetic variations
Yu Kong, Zhongcai Yao, Lingli Ren, Liqin Zhou, Jinkai Zhao, Yuanyuan Qian, Dayong Lou, Dayong Lou   +7 more
doaj   +1 more source

Diagnosis of alcoholic liver disease

World Journal of Gastroenterology, 2014
Alcohol is a hepatotoxin that is commonly consumed worldwide and is associated with a spectrum of liver injury including simple steatosis or fatty liver, alcoholic hepatitis, fibrosis, and cirrhosis. Alcoholic liver disease (ALD) is a general term used to refer to this spectrum of alcohol-related liver injuries.
Torruellas, Cara, French, Samuel W, Medici, Valentina   +2 more
openaire   +5 more sources

Role of inflammatory response in liver diseases: Therapeutic strategies

World Journal of Hepatology, 2018
Inflammation and tumorigenesis are tightly linked pathways impacting cancer development. Inflammasomes are key signalling platforms that detect pathogenic microorganisms, including hepatitis C virus (HCV) infection, and sterile stressors (oxidative ...
J. A. del Campo, P. Gallego, L. Grande
semanticscholar   +1 more source

Intestinal fungi contribute to development of alcoholic liver disease [PDF]

, 2017
This study was supported in part by NIH grants R01 AA020703, U01 AA021856 and by Award Number I01BX002213 from the Biomedical Laboratory Research & Development Service of the VA Office of Research and Development (to B.S.). K.H.
Ali Keshavarzian, An-Ming Yang, Bernd Schnabl, Bode, Chien-Sheng Chen, Claus Hellerbrand, Cristina Llorente, Derrick E. Fouts, Ece A. Mutlu, Fettweis, Fouts, Gordon D. Brown, Guadalupe Garcia-Tsao, Hal M. Hoffman, Jun Xu, Karen Beeri, Katrin Hochrath, Kelvin Moncera, Kim Freese, Lee, Lirui Wang, Liu, Manolito G. Torralba, Peng Chen, Peter Stärkel, Phillipp Hartmann, Ramon Bataller, Samuel B. Ho, Sena Bluemel, Serene M.L. Lee, Sokol, Tatiana Kisseleva, Tatsuo Inamine, Wagner, Wajahat Z. Mehal, Yamahiro, Yang, Yukinori Koyama   +37 more
core   +3 more sources

Alcoholic liver disease. An update

Annals of Hepatology, 2005
The prevalence and incidence of alcoholic liver disease are constantly evolving. Alcoholic liver disease has a wide clinical spectrum. It may progress to cirrhosis and to end-stage liver disease requiring liver transplantation. The histological manifestations range from steatosis without inflammation to liver cell injury and ultimately to fibrosis and ...
Paloma Almeda-Valdes, Nahum Méndez-Sánchez, Misael Uribe   +2 more
openaire   +4 more sources