Results 151 to 160 of about 3,036,447 (259)

Alcoholic liver diseases: current review

São Paulo Medical Journal
Moysés Mincis
doaj   +1 more source

Comment on: A cross-sectional analysis of liver disease-hypertension comorbid mortality trends in the United States, 1999-2023. [PDF]

Ann Med Surg (Lond)
Mayori F, Roy A.
europepmc   +1 more source

A Blood‐Derived Factor Rescues ALS: Platelet Factor 4 Activates OPTN‐Dependent Autophagy to Clear SOD1 Aggregates Independently of PINK1

Advanced Science, EarlyView.
Systemic platelet factor 4 (PF4) is significantly depleted in amyotrophic lateral sclerosis (ALS). Peripheral PF4 replenishment restores central proteostasis by driving OPTN‐dependent, PINK1‐independent selective autophagy in motor neurons. This intervention effectively clears toxic SOD1 aggregates, blunts glial activation, and preserves neuromuscular ...
Qingjian Xie, Yanbo Zhu, Wenhua Jiang, Haobo Xie, Yaojia Li, Mengjie Hu, Kezheng Li, Huan Yu, Yixuan Pan, Chaoyi Jiang, Xueqin Song, Dongsheng Fan, Binbin Deng   +12 more
wiley   +1 more source

Disseminated nocardiosis mimicking metastatic malignancy in a patient with alcoholic liver cirrhosis. [PDF]

IDCases
Moffa MA, Walsh TL, Rich W, Snitchler A, Shively NR.   +4 more
europepmc   +1 more source

Red Blood Cells as Endogenous Biotweezers for Optical Micromanipulation In Vivo

Advanced Science, EarlyView.
By synergistically integrating the long‐distance manipulation fiber probe (LDMFP) and endogenous red blood cells (RBCs) as biocompatible optical elements, a natural RBC biotweezer was developed for the desired microparticle manipulation and immune cell activation within living vasculature, which might offer an alternative tool for intravital optical ...
Tong Yang, Xinyu Ren, Dalin Ma, Hao Pang, Wei Chen, Kaize Cai, Mei Yuan, Bingzhi Zhang, Zufang Lin, Xiaoshuai Liu   +9 more
wiley   +1 more source

THBS1+ macrophages fuel pathogenic inflammation in alcohol-associated liver disease. [PDF]

Hepatol Commun
Xu W, Wu S, Gao J, Cheng C, Li C, Hong S, Huang J, Zhang J, An C, Wu M, Li X, Wang X, Zhang Y, Wang H, Kong D, He W.   +15 more
europepmc   +1 more source

Miro1 Protects Against Acute Kidney Injury Through Modulating Mitochondrial Homeostasis via Interaction With Sirt6

Advanced Science, EarlyView.
Ischemia‐reperfusion reduces Sirt6 activity, thereby increasing Miro1 acetylation. Hyperacetylated Miro1 exhibits perinuclear distribution and degradation, thereby inducing mitochondrial dysfunction and promoting apoptosis in renal tubular epithelial cells. This pathway reveals a mechanistic link between Sirt6‐mediated deacetylation and Miro1 stability
Lin Wu, Qing Li, Yiyang Xu, Zitao Wang, Hua Shu, Yangfan Wu, Fang Lu, Zhimin Huang, Bo Zhang, Hongwei Liang, Changying Xing, Huijuan Mao, Yanggang Yuan   +12 more
wiley   +1 more source

Stigmatizing language in alcohol-associated cirrhosis open notes: Persistent but declining. [PDF]

Hepatol Commun
Deng J, Salej Duran L, Kyalwazi B, Emebo D, Zhang W, Turer RW, Bain AP, Yekkaluri S, Cotter TG, Singal AG, Louissaint J.   +10 more
europepmc   +1 more source

Engineered Xenogeneic Bone Scaffold with IL‐10 Nanodelivery System: Immunomodulation and BMSC Fate Programming for Skull Defect Repair

Advanced Science, EarlyView.
A multifunctional regenerative composite is constructed by 3D‐printing thermosensitive PNIPAM hydrogel embedded with MPDA@IL‐10 nanoparticles and autologous BMSCs onto antigen‐depleted porcine bone matrix for beagle critical‐sized skull defect reconstruction.
Weihao Lv, Lei Zhang, Fei Fei, Zhibin Wu, Xiuquan Wu, Ya‐nan Dou, Yihao Fu, Hao Chang, Yujie Qiang, Huaxia Xie, Ni An, Leiying Chen, Hongchen Zhang, Min‐Wen Zheng, Hongqing Chen, Xia Li, Zhou Fei   +16 more
wiley   +1 more source

Trends in the etiology of acute insult and underlying chronic liver disease in patients with acute-on-chronic liver failure: A retrospective study in Southwest China (2020-2023). [PDF]

Medicine (Baltimore)
Fang Y, Dai H, Li Q, Wang D, Liu J, Liu Y.   +5 more
europepmc   +1 more source