Results 21 to 30 of about 3,036,447 (259)

Ferroptosis in Chronic Liver Diseases: Opportunities and Challenges

open access: yesFrontiers in Molecular Biosciences, 2022
Ferroptosis, an iron-dependent non-apoptotic cell death characterized by lipid peroxidation, is a cell death pathway discovered in recent years. Ferroptosis plays an important role in tumors, ischemia-reperfusion injury, neurological diseases, blood ...
Xiaoxi Zhou   +16 more
doaj   +1 more source

Adipokines and redox signaling: impact on fatty liver disease. [PDF]

open access: yes, 2011
Adipokines (adipose tissue cytokines) are polypeptide factors secreted by adipose tissue in a highly regulated manner. The 'classical' adipokines (leptin, adiponectin, and resistin) are expressed only by adipocytes, but other adipokines have been shown ...
Marra, Fabio.   +2 more
core   +1 more source

The db mouse as a model for steatohepatitis [PDF]

open access: yes, 2006
Includes bibliographical references.Fatty liver disease is a collective phrase for a spectrum of diseases characterised by increased liver fat content.
Sutherland, Jason Robert
core   +1 more source

Necroptosis in ischemia-reperfusion injury of lean and steatotic livers

open access: yesLiver Research, 2019
Hepatic ischemia-reperfusion (IR) injury is a major complication during liver transplantation, liver resection, and other clinical situations. Increased hepatic IR injury in steatotic livers is a major reason for rejecting the use of steatotic livers for
Hua Sun   +3 more
doaj   +1 more source

Alcoholic liver disease. Clinical example

open access: yesМедицинский совет, 2020
Alcoholic liver disease (ALD) is one of the major liver diseases associated with high mortality rates. There are about 3 million alcohol-related deaths worldwide every year.
T. E. Polunina
doaj   +1 more source

Progress and Prospects of Non-Canonical NF-κB Signaling Pathway in the Regulation of Liver Diseases

open access: yesMolecules, 2022
Non-canonical nuclear factor kappa B (NF-κB) signaling pathway regulates many physiological and pathological processes, including liver homeostasis and diseases.
Li Tao   +3 more
doaj   +1 more source

Non-alcoholic fatty liver disease is associated with an increased incidence of atrial fibrillation in patients with type 2 diabetes

open access: yes, 2013
BackgroundThe relationship between non-alcoholic fatty liver disease (NAFLD) and atrial fibrillation (AF) in type 2 diabetes is currently unknown. We examined the relationship between NAFLD and risk of incident AF in people with type 2 diabetes.Methods ...
Zoppini Giacomo   +39 more
core   +1 more source

Alcoholic liver disease: Current insights into cellular mechanisms [PDF]

open access: yes, 2021
Alcoholic liver disease (ALD) due to chronic alcohol consumption is a significant global disease burden and a leading cause of mortality. Alcohol abuse induces a myriad of aberrant changes in hepatocytes at both the cellular and molecular level. Although
Patel, V.   +2 more
core   +1 more source

The Role of Nrf2 in Liver Disease: Novel Molecular Mechanisms and Therapeutic Approaches

open access: yesFrontiers in Pharmacology, 2019
Oxidative stress and inflammation are the most important pathogenic events in the development and progression of liver diseases. Nuclear erythroid 2-related factor 2 (Nrf2) is the master regulator of the cellular protection via induction of anti ...
Dongwei Xu   +6 more
doaj   +1 more source

A Review of the Effects of Omega-3 and Omega-6 on Alcoholic and Non-Alcoholic Fatty Liver [PDF]

open access: yes
Non-alcoholic fatty liver disease (NAFLD) is characterized by fat accumulation in the liver not caused by excessive alcohol consumption. In contrast, alcoholic liver disease (ALD) is directly caused by it.
Darvishi, Mohammad   +6 more
core   +1 more source

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