Results 61 to 70 of about 3,036,447 (259)

Impact of high cholesterol and endoplasmic reticulum stress on metabolic diseases: An updated mini-review

Redox Biology, 2017
Endoplasmic reticulum (ER) is the major site of protein folding and calcium storage. Beside the role of ER in protein homeostasis, it controls the cholesterol production and lipid-membrane biosynthesis as well as surviving and cell death signaling ...
Erdi Sozen, Nesrin Kartal Ozer
doaj   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio, Desiree Latella, Lilla Bonanno, Paulo Cezar Rocha dos Santos, Marcos Maldonado‐Díaz, Meir Plotnik, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò   +8 more
wiley   +1 more source

Features of therapeutic options for the treatment of non-alcoholic fatty liver disease and carbohydrate metabolism disorders

Лечащий Врач
Background. Diabetes mellitus is one of the most common diseases worldwide, and non-alcoholic fatty liver disease is recognized as the most common chronic liver disease worldwide.
N. A. Petunina, M. E. Telnova, E. V. Goncharova, I. A. Kuzina   +3 more
doaj   +1 more source

Role and Mechanisms of Mitophagy in Liver Diseases

Cells, 2020
The mitochondrion is an organelle that plays a vital role in the regulation of hepatic cellular redox, lipid metabolism, and cell death. Mitochondrial dysfunction is associated with both acute and chronic liver diseases with emerging evidence indicating ...
Xiaowen Ma, Tara McKeen, Jianhua Zhang, Wen-Xing Ding   +3 more
doaj   +1 more source

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller, Vanessa Vallejo, Mónica Povedano Panadés, Orla Hardiman, Véronique Danel‐Brunaud, Senda Ajroud‐Driss, Philippe Couratier, Jeremy Shefner, Anna Gokey, Mike DiCesare, Erin Lennox, Jens Praestgaard, Lucie Brujin, Peggy Allred, Ram Miller   +14 more
wiley   +1 more source

The utility of liver function tests for mortality prediction within one year in primary care using the algorithm for liver function investigations (ALFI) [PDF]

, 2012
BACKGROUND: Although liver function tests (LFTs) are routinely measured in primary care, raised levels in patients with no obvious liver disease may trigger a range of subsequent expensive and unnecessary management plans.
Roderick Paul, Donnan, Peter T, John F. Dillon (110507), Stephen D Ryder, McLernon, DJ, Rosenberg, WM, McLernon, D.J., McLernon David J., Roderick, P., William M. Rosenberg (110512), Roderick, Paul, Donnan, PT, Dillon, John F.; id_orcid, McLernon, David J., David J McLernon, Rosenberg, William M, Paul Roderick, Donnan, Peter T.; id_orcid, Sullivan, F.M., Dillon, J.F., Ryder, Stephen D., Sullivan, Frank M, Ryder, S.D., McLernon, David J, Rosenberg, William M., Dillon, John F., John F Dillon, Peter T. Donnan (110517), Donnan, Peter T., Roderick, P, Paul Roderick (14856), Donnan, P.T., Sullivan, FM, Ryder Stephen D., Sullivan Frank M., David J. McLernon (110505), Donnan Peter T., Peter T Donnan, Dillon, John F, Rosenberg, W.M., Frank M Sullivan, Rosenberg William M., Ryder, SD, Dillon, JF, Frank M. Sullivan (110508), William M Rosenberg, Sullivan, Frank M., Ryder, Stephen D, Dillon John F., Stephen D. Ryder (110515)   +49 more
core   +1 more source

Metabolically associated fatty liver disease. What is the danger of a "safe" disease? Pathogenesis of cardiovascular complications

Лечащий Врач
Background. Nonalcoholic fatty liver disease is most often a latent disease with absent or mild clinical manifestations. It is usually detected as an incidental finding when transaminase levels are elevated or imaging signs of fatty liver degeneration ...
M. A. Isaikina, O. Yu. Isaykina, O. Yu. Trushina   +2 more
doaj   +1 more source

Obesity and metabolic abnormalities as risks of alcoholic fatty liver in men: NAGALA study

BMC Gastroenterology, 2021
Background Hepatic steatosis has a pivotal role in the development of chronic liver diseases, even in alcohol-related liver disease. Alcoholic fatty liver disease is an important phenotype among alcohol-related liver diseases. While metabolic syndrome is
Yuta Yoshimura, Masahide Hamaguchi, Yoshitaka Hashimoto, Takuro Okamura, Naoko Nakanishi, Akihiro Obora, Takao Kojima, Michiaki Fukui   +7 more
doaj   +1 more source

Factors Associated With the Rising Trend in Self‐Reported Cognitive Disability Among U.S. Adults Aged 18–39 From 2013–2024

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Building on our prior Behavioral Risk Factor Surveillance System analysis identifying adults aged 18–39 as the primary driver of the national increase in self‐reported cognitive disability, we examined factors associated with this rise using 2013–2024 U.S. BRFSS data. Methods We analyzed U.S.
Adam de Havenon, Ka‐Ho Wong, Mirriam Mananah, Christopher D. Anderson, Ada Fenick, Amy Arnsten, Arman Fesharaki‐Zadeh, James C. McPartland, Mary L. Adams, Kevin N. Sheth   +9 more
wiley   +1 more source

Garlic and Liver Diseases

, 2018
Oxidative stress is involved in all kinds of liver diseases, from acute liver injury to malignancy, orchestrated by other important pathological events, such as inflammation, apoptosis, and fibrosis.
Rui Zhang, George L. Tipoe, Zou, LL, Zhang, R, Hao Gao, Jia Xiao, Xiao, J, Liangliang Zou, Gao, H, Tipoe, GL   +9 more
core   +1 more source